Antiviral drug discovery: preparing for the next pandemic.
Chem Soc Rev
; 50(6): 3647-3655, 2021 Mar 21.
Article
in English
| MEDLINE | ID: covidwho-1057718
ABSTRACT
Clinically approved antiviral drugs are currently available for only 10 of the more than 220 viruses known to infect humans. The SARS-CoV-2 outbreak has exposed the critical need for compounds that can be rapidly mobilised for the treatment of re-emerging or emerging viral diseases, while vaccine development is underway. We review the current status of antiviral therapies focusing on RNA viruses, highlighting strategies for antiviral drug discovery and discuss the challenges, solutions and options to accelerate drug discovery efforts.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
RNA, Viral
/
Drug Discovery
/
Molecular Targeted Therapy
/
Pandemics
/
COVID-19 Drug Treatment
Type of study:
Prognostic study
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
Chem Soc Rev
Year:
2021
Document Type:
Article
Affiliation country:
D0cs01118e
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