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Outbreak of respiratory infection: Ncov-2019 current status and its impact on global health
Current Respiratory Medicine Reviews ; 16(3):156-164, 2020.
Article in English | Scopus | ID: covidwho-1058347
ABSTRACT
Novel coronavirus-2019 (nCoV-2019) emerged as a potentially infectious respiratory disease caused by newly discovered β-coronavirus. nCoV-19 has emerged as a global pandemic due to the rapid transmission and high infection rate commonly involved in acute respiratory ill-ness. Literature search includes various databases like Google Scholar, PubMed, ScienceDirect, and Scopus for studies published using a different combination of keywords “coronavius”, “COVID-19”, “SARS”, “MERS”, “antiviral drugs”, “vaccines”, and “immunity”. We collected epidemiology data from the Worldometer portal (data available till 9 October, 2020). Fever, dry cough, dyspnea, sore throat, or fatigue are common clinical symptoms of the infection. Cytotoxic T-cells and T-helper cells plus Cytotoxic T cells (CD8+) account for maximum (approximately 80%) of total infiltrate in the pulmonary region of the affected nCoV individuals and act as a significant contributor to the clearance of the infection. This review intends to outline the literature con-cerning the mode of actual transmission, immune response, and possible therapeutic approach against the virus. © 2020 Bentham Science Publishers.

Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Experimental Studies Language: English Journal: Current Respiratory Medicine Reviews Year: 2020 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Experimental Studies Language: English Journal: Current Respiratory Medicine Reviews Year: 2020 Document Type: Article