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Effect of SARS-CoV-2 coinfection was not apparent on the dynamics of chronic hepatitis B infection.
Yu, Rentao; Tan, Shun; Dan, Yunjie; Lu, Yanqiu; Zhang, Juan; Tan, Zhaoxia; He, Xiaoqing; Xiang, Xiaomei; Zhou, Yi; Guo, Yanzhi; Deng, Guohong; Chen, Yaokai; Tan, Wenting.
  • Yu R; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China; Department of Infectious Diseases, The General Hospital of Western Theater Command, Chengdu, Sichuan, 610083, China.
  • Tan S; Intensive Care Unit, Chongqing Public Health Medical Center, Chongqing, 400036, China.
  • Dan Y; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China; Chongqing Key Laboratory for Research of Infectious Diseases, Chongqing, 400038, China.
  • Lu Y; Division of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, 400036, China.
  • Zhang J; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China; Chongqing Key Laboratory for Research of Infectious Diseases, Chongqing, 400038, China.
  • Tan Z; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China; Chongqing Key Laboratory for Research of Infectious Diseases, Chongqing, 400038, China.
  • He X; Division of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, 400036, China.
  • Xiang X; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China; Chongqing Key Laboratory for Research of Infectious Diseases, Chongqing, 400038, China.
  • Zhou Y; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China; Chongqing Key Laboratory for Research of Infectious Diseases, Chongqing, 400038, China.
  • Guo Y; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China; Chongqing Key Laboratory for Research of Infectious Diseases, Chongqing, 400038, China.
  • Deng G; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China; Chongqing Key Laboratory for Research of Infectious Diseases, Chongqing, 400038, China.
  • Chen Y; Division of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, 400036, China. Electronic address: yaokaichen@hotmail.com.
  • Tan W; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China; Chongqing Key Laboratory for Research of Infectious Diseases, Chongqing, 400038, China. Electronic address: tan_wenting@126.com.
Virology ; 553: 131-134, 2021 01 15.
Article in English | MEDLINE | ID: covidwho-1059938
ABSTRACT
In patients coinfected with SARS-CoV-2 and HBV, liver injury was common. However, the interactions between SARS-CoV-2 and HBV coinfection remained unknown. Sixty-seven COVID-19 patients from the previous cohort were enrolled and classified into 2 groups (7 with HBsAg+ and 60 with HBsAg-). The association of HBV- and SARS-CoV-2-related markers were analyzed. During the acute course of SARS-CoV-2 infection, markers of HBV replication did not extensively fluctuate during SARS-CoV-2 infection. Coinfection with HBV did not extend the viral shedding cycle or incubation periods of SARS-CoV-2. Effects of SARS-CoV-2 on the dynamics of chronic HBV infection seemed not apparent. SARS-CoV-2 infection would not be the source of HBV reactivation in these individuals.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Hepatitis B, Chronic / Coinfection / SARS-CoV-2 / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Virology Year: 2021 Document Type: Article Affiliation country: J.virol.2020.11.012

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Hepatitis B, Chronic / Coinfection / SARS-CoV-2 / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Virology Year: 2021 Document Type: Article Affiliation country: J.virol.2020.11.012