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Moving Beyond the Momentum: Innovative Approaches to Clinical Trial Implementation.
Eng, Cathy; Chen, Emerson Y; Rogers, Jane; Lewis, Mark; Strosberg, Jonathan; Thota, Ramya; Krishnamurthi, Smitha; Oberstein, Paul; Govindarajan, Rang; Buchschacher, Gary; Patel, Sandip; Sohal, Davendra; Al-Toubah, Taymeyah; Philip, Philip; Dasari, Arvind; Kennecke, Hagan; Stein, Stacey.
  • Eng C; Vanderbilt-Ingram Cancer Center, Nashville, TN.
  • Chen EY; Division of Hematology and Oncology, Oregon Health and Science University, Knight Cancer Institute, Portland, OR.
  • Rogers J; University of Texas MD Anderson Cancer Center Pharmacy Clinical Programs, Houston, TX.
  • Lewis M; Intermountain Healthcare, Salt Lake, UT.
  • Strosberg J; Moffitt Cancer Center, Tampa, FL.
  • Thota R; Intermountain Healthcare, Salt Lake, UT.
  • Krishnamurthi S; Cleveland Clinic Taussig Cancer Center, Cleveland, OH.
  • Oberstein P; New York University Langone Health, New York, NY.
  • Govindarajan R; Winthrop P. Rockefeller Cancer Institute, University of Arkansas, Little Rock, AR.
  • Buchschacher G; Kaiser Permanente, Los Angeles Cancer Clinic, Los Angeles, CA.
  • Patel S; Moores Cancer Center, UC San Diego Health, La Jolla, CA.
  • Sohal D; University of Cincinnati Health Barrett Cancer Center, Cincinnati, OH.
  • Al-Toubah T; Moffitt Cancer Center, Tampa, FL.
  • Philip P; Karmanos Cancer Center, Detroit, MI.
  • Dasari A; University of Texas MD Anderson Cancer Center, Houston, TX.
  • Kennecke H; Virginia Mason Cancer Center, Seattle, WA.
  • Stein S; Smilow Cancer Center, Yale School of Medicine, New Haven, CT.
JCO Oncol Pract ; 17(10): 607-614, 2021 10.
Article in English | MEDLINE | ID: covidwho-1060961
Semantic information from SemMedBD (by NLM)
1. Malignant Neoplasms PROCESS_OF Patients
Subject
Malignant Neoplasms
Predicate
PROCESS_OF
Object
Patients
2. COVID-19 DISRUPTS physician patient interaction
Subject
COVID-19
Predicate
DISRUPTS
Object
physician patient interaction
3. Malignant Neoplasms PROCESS_OF Patients
Subject
Malignant Neoplasms
Predicate
PROCESS_OF
Object
Patients
4. COVID-19 DISRUPTS physician patient interaction
Subject
COVID-19
Predicate
DISRUPTS
Object
physician patient interaction
ABSTRACT
Despite efforts to enhance enrollment and the merger of national cooperative groups, < 5% of patients with cancer will enroll into a clinical trial. Additionally, clinical trials are affected by a lack of diversity inclusive of minority patients, rural residents, or low-income individuals. COVID-19 further exacerbated known barriers of reduced physician-patient interaction, physician availability, trial activation and enrollment, financial resources, and capacity for conducting research. Based on the cumulative insight of academic and community clinical researchers, we have created a white paper identifying existing challenges in clinical trial conduct and have provided specific recommendations of sustainable modifications to improve efficiency in the activation and conduct of clinical trials with an overarching goal of providing improved access and care to our patients with cancer.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Physicians / COVID-19 / Neoplasms Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: JCO Oncol Pract Year: 2021 Document Type: Article Affiliation country: Op.20.00701

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Physicians / COVID-19 / Neoplasms Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: JCO Oncol Pract Year: 2021 Document Type: Article Affiliation country: Op.20.00701