Frequency of severe vitamin D deficiency and its association with mortality in patients with corona virus disease
Pakistan Journal of Medical and Health Sciences
; 14(4):1206-1208, 2020.
Article
in English
| Scopus | ID: covidwho-1061666
ABSTRACT
Aim:
To determine the frequency of severe vitamin D deficiency and its association with mortality in patients presented with Covid-19. StudyDesign:
Cross-sectional/Observational Place and Duration of Study Chandka Medical College Hospital, Larkana and Gambat Medical College Hospital, Gambat from 1st March 2020 to 31st August 2020Methodology:
One hundred and twenty five patients of both genders diagnosed to have severe covid-19 disease by real time PCR were analyzed. Patient’s ages were ranging from 15 years to 70 years. Detailed demographics were recorded after taking written consent. 5 ml blood sample was taken from all the patients to examine the vitamin D level. Severe Vitamin D deficiency was defined as 25(OH)D <25 nmol/L (10 ng/dL). Association between mortality and severe vitamin D deficiency was examined.Results:
Seventy five (60%) were males while 50 (40%) were females with mean age 45.58±15.66 years. Severe vitamin D deficiency was observed in 57 (45.6%) patients. Overall mortality was found in 14 (11.2%) patients, Among 57 patients with severe vitamin D deficiency 12 (9.6%) were died while patients with no vitamin D deficiency 2/68 (1.6%), a significant association was observed between severe vitamin D deficiency and mortality in patients with covid-19 disease with p-value <0.05.Conclusion:
There was strong relationship between severe vitamin-D deficiency and mortality in patients with covid-19 disease. © 2020 Lahore Medical And Dental College. All rights reserved.
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Collection:
Databases of international organizations
Database:
Scopus
Language:
English
Journal:
Pakistan Journal of Medical and Health Sciences
Year:
2020
Document Type:
Article
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