A comprehensive review on the biological interest of quinoline and its derivatives.
Bioorg Med Chem
; 32: 115973, 2021 02 15.
Article
in English
| MEDLINE | ID: covidwho-1064894
ABSTRACT
Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a significant assembly motif for the development of new drug entities. Quinoline and its derivatives tested with diverse biological activity constitute an important class of compounds for new drug development. Therefore, many scientific communities have developed these compounds as intent structure and evaluated their biological activities. The present, review provides brief natural sources of quinoline and including a new extent of quinoline-based marketed drugs. This review also confers information about the biological activities of quinoline derivatives such as antibacterial, antifungal, antimycobacterial, antiviral, anti-protozoal, antimalarial, anticancer, cardiovascular, CNS effects, antioxidant, anticonvulsant, analgesic, anti-inflammatory, anthelmintic and miscellaneous activities.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Anti-Inflammatory Agents, Non-Steroidal
/
Analgesics
/
Anti-Infective Agents
/
Antineoplastic Agents
/
Antioxidants
/
Antiprotozoal Agents
Type of study:
Experimental Studies
Limits:
Humans
Language:
English
Journal:
Bioorg Med Chem
Journal subject:
Biochemistry
/
Chemistry
Year:
2021
Document Type:
Article
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