Etoposide as Salvage Therapy for Cytokine Storm Due to Coronavirus Disease 2019.
Chest
; 159(1): e7-e11, 2021 01.
Article
in English
| MEDLINE | ID: covidwho-1064922
ABSTRACT
Coronavirus disease 2019 (COVID-19) has resulted in significant morbidity and mortality because of a lack of effective therapies. Therapeutic strategies under investigation target the overactive cytokine response with anti-cytokine or immunomodulators therapies. We present a unique case of severe cytokine storm resistant to multiple anti-cytokine therapies, but eventually responsive to etoposide. Thus, etoposide may have a role as salvage therapy in treatment of cytokine storm in COVID-19. To our knowledge, this is the first reported case of use of etoposide in COVID-19.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Etoposide
/
Cytokine Release Syndrome
/
COVID-19
Type of study:
Case report
/
Prognostic study
Topics:
Long Covid
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Chest
Year:
2021
Document Type:
Article
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