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Characteristics of registered clinical trials on traditional Chinese medicine for coronavirus disease 2019 (COVID-19): A scoping review.
Luo, Hui; Yang, Ming; Tang, Qiao-Ling; Hu, Xiao-Yang; Willcox, Merlin L; Liu, Jian-Ping.
  • Luo H; Institute for Tibetan Medicine, China Tibetology Research Center, Beijing 100101, China.
  • Yang M; Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
  • Tang QL; Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
  • Hu XY; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
  • Willcox ML; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
  • Liu JP; School of Primary Care, Population Sciences and Medical Education, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton SO16 5ST, United Kingdom.
Eur J Integr Med ; 41: 101251, 2021 Jan.
Article in English | MEDLINE | ID: covidwho-1065082
Semantic information from SemMedBD (by NLM)
1. Registration TREATS COVID-19
Subject
Registration
Predicate
TREATS
Object
COVID-19
2. qingfei paidu decoction TREATS COVID-19
Subject
qingfei paidu decoction
Predicate
TREATS
Object
COVID-19
3. Registration TREATS COVID-19
Subject
Registration
Predicate
TREATS
Object
COVID-19
4. qingfei paidu decoction TREATS COVID-19
Subject
qingfei paidu decoction
Predicate
TREATS
Object
COVID-19
ABSTRACT

INTRODUCTION:

Traditional Chinese medicine (TCM) has been fully committed to the treatment of coronavirus disease 2019 (COVID-19) in China. An increasing number of clinical trials have been registered to evaluate the effects of TCM for COVID-19. The aim of this study was to review the existing TCM clinical trial registrations and identify potentially promising and available TCM therapies, in order to provide a reference for the global management of COVID-19.

METHODS:

All clinical trials on TCM for COVID-19 registered in registry platforms worldwide were searched. The data of registration temporal trend, design, objective, interventions, and relevant information were reviewed and summarized.

RESULTS:

161 TCM trials were identified from three registries (January 26 to May 14 2020,). Of these, 94 (58.4%) were randomized controlled trials and 114 trials (70.8%) assessed therapeutic effects; while the remainder focused on prevention, rehabilitation, and the epidemiology of TCM syndromes. Eight trials (5.0%) had completed their recruitment. TCM interventions with potential for further evaluation in terms of prevention were moxibustion, Huoxiang Zhengqi pill and Jinye Baidu granules. For treatment of COVID-19, Qingfei Paidu decoction, Huashi Baidu decoction, Lianhua Qingwen capsules, Toujie Quwen granules and Xiyanping injection, and Xuebijing injection were to be tested for their therapeutic effects and symptoms relief. For rehabilitation, Tai Chi and Liuzijue were to be tested for improving patients' lung function.

CONCLUSION:

Some potentially promising TCM interventions have been identified and deserve further evaluation to establish their evidence base, particularly on populations outside of China.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Controlled clinical trial / Prognostic study / Randomized controlled trials / Reviews Topics: Traditional medicine Language: English Journal: Eur J Integr Med Year: 2021 Document Type: Article Affiliation country: J.eujim.2020.101251

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Controlled clinical trial / Prognostic study / Randomized controlled trials / Reviews Topics: Traditional medicine Language: English Journal: Eur J Integr Med Year: 2021 Document Type: Article Affiliation country: J.eujim.2020.101251