Optical coherence tomography angiography findings in patients with COVID-19.
Can J Ophthalmol
; 56(2): 83-87, 2021 Apr.
Article
in English
| MEDLINE | ID: covidwho-1065297
ABSTRACT
OBJECTIVE:
To examine the changes in choriocapillaris and retina caused by coronavirus disease 2019 (COVID-19) by comparing optical coherence tomography angiography (OCTA) findings of COVID-19 patients and healthy controls.METHODS:
The study and control groups consisted of 54 eyes of 27 participants, each. Patients and controls underwent OCTA examination. Foveal zone vessel density and parafoveal zone vessel density (for 4 quadrants nasal, temporal, superior, inferior) were calculated for both superficial and deep capillary plexuses. Additionally, choriocapillaris flow and foveal avascular zone areas were calculated.RESULTS:
For the parafoveal area in the study group, vessel density was significantly lower in the superior and nasal quadrants of the superficial capillary plexus and in all quadrants of the deep capillary plexus compared with controls (p < 0.05 for all). The study group had significantly higher choriocapillaris flow area values compared with controls (pâ¯=â¯0.042).CONCLUSION:
Reduced vessel density of the retinal capillary plexus was detected in COVID-19 patients who may be at risk for retinal vascular complications.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Retinal Diseases
/
Retinal Vessels
/
Choroid Diseases
/
Eye Infections, Viral
/
Choroid
/
SARS-CoV-2
/
COVID-19
Type of study:
Diagnostic study
/
Experimental Studies
/
Prognostic study
/
Randomized controlled trials
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
/
Young adult
Language:
English
Journal:
Can J Ophthalmol
Year:
2021
Document Type:
Article
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