COVID-19 Infection in Men on Testosterone Replacement Therapy.
J Sex Med
; 18(1): 215-218, 2021 01.
Article
in English
| MEDLINE | ID: covidwho-1065396
ABSTRACT
BACKGROUND:
Men who contract coronavirus disease 2019 (COVID-19) appear to have worse clinical outcomes compared with women which raises the possibility of androgen-dependent effects.AIM:
We sought to determine if testosterone replacement therapy (TRT) is associated with worse clinical outcomes.METHODS:
Through a retrospective chart review, we identified 32 men diagnosed with COVID-19 and on TRT. They were propensity score matched to 63 men diagnosed with COVID-19 and not on TRT. Data regarding comorbidities and endpoints such as hospital admission, intensive care unit admission, ventilator utilization, thromboembolic events, and death were extracted. Chi-square and Kruskal-Wallis tests examined differences in categorical and continuous variables, respectively. Logistic regression analysis tested the relationship between TRT status and the study endpoints.RESULTS:
There were no statistically significant differences between the 2 groups, and TRT was not a predictor of any of the endpoints on multivariate analysis.CONCLUSION:
These results suggest that TRT is not associated with a worse clinical outcome in men diagnosed with COVID-19. Rambhatla A, Bronkema CJ, Corsi N, et al. COVID-19 Infection in Men on Testosterone Replacement Therapy. J Sex Med 2021;18215-218.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Hypogonadism
Type of study:
Case report
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
/
Male
Language:
English
Journal:
J Sex Med
Journal subject:
Gynecology
/
Reproductive Medicine
/
Urology
Year:
2021
Document Type:
Article
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