Your browser doesn't support javascript.
CRISPR Systems for COVID-19 Diagnosis.
Rahimi, Hossein; Salehiabar, Marziyeh; Barsbay, Murat; Ghaffarlou, Mohammadreza; Kavetskyy, Taras; Sharafi, Ali; Davaran, Soodabeh; Chauhan, Subhash C; Danafar, Hossein; Kaboli, Saeed; Nosrati, Hamed; Yallapu, Murali M; Conde, João.
  • Rahimi H; Department of Medical Biotechnology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
  • Salehiabar M; Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
  • Barsbay M; Drug Applied Research Center, Tabriz University of Medical Sciences, P.O. Box 51656-65811, Tabriz, Iran.
  • Ghaffarlou M; Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, Drohobych, Ukraine; Baku, Azerbaijan.
  • Kavetskyy T; Hacettepe University, Department of Chemistry, Beytepe, Ankara 06800, Turkey.
  • Sharafi A; Hacettepe University, Department of Chemistry, Beytepe, Ankara 06800, Turkey.
  • Davaran S; Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, Drohobych, Ukraine; Baku, Azerbaijan.
  • Chauhan SC; Department of Surface Engineering, The John Paul II Catholic University of Lublin, 20-950 Lublin, Poland.
  • Danafar H; Drohobych Ivan Franko State Pedagogical University, 82100 Drohobych, Ukraine.
  • Kaboli S; Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
  • Nosrati H; Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, Drohobych, Ukraine; Baku, Azerbaijan.
  • Yallapu MM; Drug Applied Research Center, Tabriz University of Medical Sciences, P.O. Box 51656-65811, Tabriz, Iran.
  • Conde J; Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, Drohobych, Ukraine; Baku, Azerbaijan.
ACS Sens ; 6(4): 1430-1445, 2021 04 23.
Article in English | MEDLINE | ID: covidwho-1065799
ABSTRACT
The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019, which has spread rapidly and become a global pandemic. The number of cases of COVID-19 and its associated mortality have raised serious concerns worldwide. Early diagnosis of viral infection undoubtedly allows rapid intervention, disease management, and substantial control of the rapid spread of the disease. Currently, the standard approach for COVID-19 diagnosis globally is the RT-qPCR test; however, the limited access to kits and associated reagents, the need for specialized lab equipment, and the need for highly skilled personnel has led to a detection slowdown. Recently, the development of clustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostic systems has reshaped molecular diagnosis. The benefits of the CRISPR system such as speed, precision, specificity, strength, efficiency, and versatility have inspired researchers to develop CRISPR-based diagnostic and therapeutic methods. With the global COVID-19 outbreak, different groups have begun to design and develop diagnostic and therapeutic programs based on the efficient CRISPR system. CRISPR-based COVID-19 diagnostic systems have advantages such as a high detection speed (i.e., 30 min from raw sample to reach a result), high sensitivity and precision, portability, and no need for specialized laboratory equipment. Here, we review contemporary studies on the detection of COVID-19 based on the CRISPR system.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Clustered Regularly Interspaced Short Palindromic Repeats / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Randomized controlled trials Limits: Humans Language: English Journal: ACS Sens Year: 2021 Document Type: Article Affiliation country: Acssensors.0c02312

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Clustered Regularly Interspaced Short Palindromic Repeats / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Randomized controlled trials Limits: Humans Language: English Journal: ACS Sens Year: 2021 Document Type: Article Affiliation country: Acssensors.0c02312