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Effective control of SARS-CoV-2 transmission in Wanzhou, China.
Shi, Qiuling; Hu, Yaoyue; Peng, Bin; Tang, Xiao-Jun; Wang, Wei; Su, Kun; Luo, Chao; Wu, Bo; Zhang, Fan; Zhang, Yong; Anderson, Benjamin; Zhong, Xiao-Ni; Qiu, Jing-Fu; Yang, Cheng Yong; Huang, Ai-Long.
  • Shi Q; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
  • Hu Y; State Key Laboratory of Ultrasound in Medicine and Engineering, Chongqing Medical University, Chongqing, China.
  • Peng B; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
  • Tang XJ; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
  • Wang W; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
  • Su K; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
  • Luo C; Center for Disease Control and Prevention, Chongqing, China.
  • Wu B; Wanzhou District Center for Disease Control and Prevention, Chongqing, China.
  • Zhang F; Wanzhou District Center for Disease Control and Prevention, Chongqing, China.
  • Zhang Y; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
  • Anderson B; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
  • Zhong XN; Global Health Research Center, Duke Kunshan University, Kunshan, China.
  • Qiu JF; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
  • Yang CY; School of Public Health and Management, Chongqing Medical University, Chongqing, China. jfqiu@126.com.
  • Huang AL; Ausper Biopharma, Hangzhou, China. thechrisyang@gmail.com.
Nat Med ; 27(1): 86-93, 2021 01.
Article in English | MEDLINE | ID: covidwho-1065912
ABSTRACT
The effectiveness of control measures to contain coronavirus disease 2019 (COVID-19) in Wanzhou, China was assessed. Epidemiological data were analyzed for 183 confirmed COVID-19 cases and their close contacts from five generations of transmission of severe acute respiratory syndrome coronavirus 2 throughout the entire COVID-19 outbreak in Wanzhou. Approximately 67.2% and 32.8% of cases were symptomatic and asymptomatic, respectively. Asymptomatic and presymptomatic transmission accounted for 75.9% of the total recorded transmission. The reproductive number was 1.64 (95% confidence interval 1.16-2.40) for G1-to-G2 transmission, decreasing to 0.31-0.39 in later generations, concomitant with implementation of rigorous control measures. Substantially higher infection risk was associated with contact within 5 d after the infectors had been infected, frequent contact and ≥8 h of contact duration. The spread of COVID-19 was effectively controlled in Wanzhou by breaking the transmission chain through social distancing, extensive contact tracing, mass testing and strict quarantine of close contacts.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Communicable Disease Control / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Adult / Child / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Nat Med Journal subject: Molecular Biology / Medicine Year: 2021 Document Type: Article Affiliation country: S41591-020-01178-5

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Communicable Disease Control / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Adult / Child / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Nat Med Journal subject: Molecular Biology / Medicine Year: 2021 Document Type: Article Affiliation country: S41591-020-01178-5