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Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults.
Madera, Sharline; Crawford, Emily; Langelier, Charles; Tran, Nam K; Thornborrow, Ed; Miller, Steve; DeRisi, Joseph L.
  • Madera S; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA, USA. sharline.madera@ucsf.edu.
  • Crawford E; Chan-Zuckerberg Biohub, San Francisco, CA, USA.
  • Langelier C; Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA.
  • Tran NK; Department of Medicine and Biochemistry & Biophysics, University of California San Francisco, San Francisco, CA, USA.
  • Thornborrow E; Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, CA, USA.
  • Miller S; Chan-Zuckerberg Biohub, San Francisco, CA, USA.
  • DeRisi JL; Department of Pathology and Laboratory Medicine, Davis School of Medicine, University of California, Sacramento, CA, USA.
Sci Rep ; 11(1): 3044, 2021 02 04.
Article in English | MEDLINE | ID: covidwho-1065949
Preprint
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ABSTRACT
The role of children in the spread of the SARS-CoV-2 coronavirus has become a matter of urgent debate as societies in the US and abroad consider how to safely reopen schools. Small studies have suggested higher viral loads in young children. Here we present a multicenter investigation on over five thousand SARS-CoV-2 cases confirmed by real-time reverse transcription (RT) PCR assay. Notably, we found no discernable difference in amount of viral nucleic acid among young children and adults.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: RNA, Viral / Nasopharynx / Viral Load / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Observational study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: North America Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-81934-w

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Full text: Available Collection: International databases Database: MEDLINE Main subject: RNA, Viral / Nasopharynx / Viral Load / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Observational study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: North America Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-81934-w