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Extreme Exposure to Filtered Far-UVC: A Case Study†.
Eadie, Ewan; Barnard, Isla M R; Ibbotson, Sally H; Wood, Kenneth.
  • Eadie E; Scottish Photobiology Service, Photobiology Unit, NHS Tayside, Ninewells Hospital and Medical School, Dundee, UK.
  • Barnard IMR; SUPA, School of Physics & Astronomy, University of St Andrews, St Andrews, UK.
  • Ibbotson SH; Scottish Photobiology Service, Photobiology Unit, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
  • Wood K; SUPA, School of Physics & Astronomy, University of St Andrews, St Andrews, UK.
Photochem Photobiol ; 97(3): 527-531, 2021 05.
Article in English | MEDLINE | ID: covidwho-1066753
ABSTRACT
Far-UVC devices are being commercially sold as "safe for humans" for the inactivation of SARS-CoV-2, without supporting human safety data. We felt there was a need for rapid proof-of-concept human self-exposure, to inform future controlled research and promote informed discussion. A Fitzpatrick Skin Type II individual exposed their inner forearms to large radiant exposures from a filtered Krypton-Chloride (KrCl) far-UVC system (SafeZoneUVC, Ushio Inc., Tokyo, Japan) with peak emission at 222 nm. No visible skin changes were observed at 1500 mJ cm-2 ; whereas, skin yellowing that appeared immediately and resolved within 24 h occurred with a 6000 mJ cm-2 exposure. No erythema was observed at any time point with exposures up to 18 000 mJ cm-2 . These results combined with Monte Carlo Radiative Transfer computer modeling suggest that filtering longer ultraviolet wavelengths is critical for the human skin safety of far-UVC devices. This work also contributes to growing arguments for the exploration of exposure limit expansion, which would subsequently enable faster inactivation of viruses.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Skin / Ultraviolet Rays / Radiation Exposure Type of study: Case report / Experimental Studies / Observational study Limits: Adult / Humans / Male Language: English Journal: Photochem Photobiol Year: 2021 Document Type: Article Affiliation country: Php.13385

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Skin / Ultraviolet Rays / Radiation Exposure Type of study: Case report / Experimental Studies / Observational study Limits: Adult / Humans / Male Language: English Journal: Photochem Photobiol Year: 2021 Document Type: Article Affiliation country: Php.13385