Fulminant Bacillus cereus food poisoning with fatal multi-organ failure.
BMJ Case Rep
; 14(1)2021 Jan 18.
Article
in English
| MEDLINE | ID: covidwho-1066836
ABSTRACT
This case represents a rare fulminant course of fried-rice associated food poisoning in an immunocompetent person due to pre-formed exotoxin produced by Bacillus cereus, with severe manifestations of sepsis, including multi-organ (hepatic, renal, cardiac, respiratory and neurological) failure, shock, metabolic acidosis, rhabdomyolysis and coagulopathy. Despite maximal supportive measures (continuous renal replacement therapy, plasmapheresis, N-acetylcysteine infusion and blood products, and broad-spectrum antimicrobials) and input from a multidisciplinary team (consisting of infectious diseases, intensive care, gastroenterology, surgery, toxicology, immunology and haematology), mortality resulted. This case is the first to use whole genome sequencing techniques to confirm the toxigenic potential of B. cereus It has important implications for food preparation and storage, particularly given its occurrence in home isolation during the COVID-19 pandemic.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Bacillus cereus
/
Exotoxins
/
Foodborne Diseases
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
Bcr-2020-238716
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