COVID-19 infection in the palatine tonsil tissue and detritus: the detection of the virus compartment with RT-PCR.
BMJ Case Rep
; 14(2)2021 Feb 05.
Article
in English
| MEDLINE | ID: covidwho-1066839
ABSTRACT
Two patients suffering from chronic recurrent tonsillitis were reported. The first patient was confirmed infected with COVID-19, 3 weeks prior to tonsillectomy. The detritus and tonsil specimen were further analysed through real-time PCR (RT-PCR) and revealed amplification of the fragment N and ORF1ab genes of SARS-CoV-2. The second patient had a negative IgM and positive IgG antibody for COVID-19; however, the nasopharyngeal swab indicated negative for SARS-CoV-2. Tonsillectomy was performed 2 weeks after the swab; the tonsil specimen was analysed through RT-PCR and revealed amplification of the N2 and RdRp gene of SARS-CoV-2. According to both results, the presence of the SARS-CoV-2 gene remains to be detected in tonsil and/or detritus after 2-3 weeks after recovery. Hence, it is suggested that it is necessary to use adequate protection when performing tonsillectomy on early recovered patients with COVID-19. Furthermore, tonsillectomy would be more advisable to be performed after the fourth week after recovery from COVID-19.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Palatine Tonsil
/
Tonsillitis
/
COVID-19 Nucleic Acid Testing
/
COVID-19
Type of study:
Case report
/
Diagnostic study
Topics:
Long Covid
Limits:
Adult
/
Female
/
Humans
/
Male
/
Young adult
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
Bcr-2020-239108
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