Plasma microbial cell-free DNA load is associated with mortality in patients with COVID-19.

Kitsios, Georgios D; Bain, William; Al-Yousif, Nameer; Duttagupta, Radha; Ahmed, Asim A; McVerry, Bryan J; Morris, Alison

Kitsios, Georgios D; Bain, William; Al-Yousif, Nameer; Duttagupta, Radha; Ahmed, Asim A; McVerry, Bryan J; Morris, Alison.

Kitsios GD; Division of Pulmonary, Allergy and Critical Care Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh Medical Center, UPMC Montefiore Hospital, NW 628, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA. kitsiosg@upmc.edu.
Bain W; Division of Pulmonary, Allergy and Critical Care Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh Medical Center, UPMC Montefiore Hospital, NW 628, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Al-Yousif N; Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Duttagupta R; Department of Medicine, University of Pittsburgh Medical Center Mercy, Pittsburgh, PA, USA.
Ahmed AA; Karius Inc, Redwood City, CA, USA.
McVerry BJ; Karius Inc, Redwood City, CA, USA.
Morris A; Division of Pulmonary, Allergy and Critical Care Medicine, Acute Lung Injury Center of Excellence, University of Pittsburgh Medical Center, UPMC Montefiore Hospital, NW 628, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.

Respir Res ; 22(1): 24, 2021 01 20.

Article in English | MEDLINE | ID: covidwho-1067234

Subject(s)

COVID-19 Nucleic Acid Testing; COVID-19/diagnosis; Cell-Free Nucleic Acids/blood; Coinfection/diagnosis; DNA, Bacterial/blood; DNA, Viral/blood; Metagenomics; Pneumonia, Bacterial/diagnosis; SARS-CoV-2/genetics; Bacterial Load; COVID-19/blood; COVID-19/mortality; COVID-19/virology; Cell-Free Nucleic Acids/genetics; Coinfection/blood; Coinfection/microbiology; Coinfection/mortality; DNA, Bacterial/genetics; Female; Humans; Male; Middle Aged; Pneumonia, Bacterial/blood; Pneumonia, Bacterial/microbiology; Pneumonia, Bacterial/mortality; Predictive Value of Tests; Prognosis; Prospective Studies; Sequence Analysis, DNA; Viral Load

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Full text: Available Collection: International databases Database: MEDLINE Main subject: DNA, Bacterial / DNA, Viral / Pneumonia, Bacterial / Metagenomics / Coinfection / Cell-Free Nucleic Acids / COVID-19 Nucleic Acid Testing / SARS-CoV-2 / COVID-19 Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Limits: Female / Humans / Male / Middle aged Language: English Journal: Respir Res Year: 2021 Document Type: Article Affiliation country: S12931-021-01623-0

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