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Mental health before and during the COVID-19 pandemic in two longitudinal UK population cohorts.
Kwong, Alex S F; Pearson, Rebecca M; Adams, Mark J; Northstone, Kate; Tilling, Kate; Smith, Daniel; Fawns-Ritchie, Chloe; Bould, Helen; Warne, Naomi; Zammit, Stanley; Gunnell, David J; Moran, Paul A; Micali, Nadia; Reichenberg, Abraham; Hickman, Matthew; Rai, Dheeraj; Haworth, Simon; Campbell, Archie; Altschul, Drew; Flaig, Robin; McIntosh, Andrew M; Lawlor, Deborah A; Porteous, David; Timpson, Nicholas J.
  • Kwong ASF; MRC Integrative Epidemiology Unit, University of Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, UK; and Division of Psychiatry, University of Edinburgh, UK.
  • Pearson RM; MRC Integrative Epidemiology Unit, University of Bristol, UK; and Population Health Sciences, Bristol Medical School, University of Bristol, UK.
  • Adams MJ; Division of Psychiatry, University of Edinburgh, UK.
  • Northstone K; Population Health Sciences, Bristol Medical School, University of Bristol, UK.
  • Tilling K; MRC Integrative Epidemiology Unit, University of Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, UK; and Division of Psychiatry, University of Edinburgh, UK.
  • Smith D; MRC Integrative Epidemiology Unit, University of Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, UK; and Division of Psychiatry, University of Edinburgh, UK.
  • Fawns-Ritchie C; Department of Psychology, University of Edinburgh, UK.
  • Bould H; Population Health Sciences, Bristol Medical School, University of Bristol, UK; and Gloucestershire Health and Care NHS Foundation Trust, UK.
  • Warne N; Population Health Sciences, Bristol Medical School, University of Bristol, UK.
  • Zammit S; Population Health Sciences, Bristol Medical School, University of Bristol, UK; and MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK.
  • Gunnell DJ; Population Health Sciences, Bristol Medical School, University of Bristol, UK; and National Institute of Health Research Biomedical Research Centre, University of Bristol, UK.
  • Moran PA; Population Health Sciences, Bristol Medical School, University of Bristol, UK; National Institute of Health Research Biomedical Research Centre, University of Bristol, UK; and Avon and Wiltshire Mental Health Partnership NHS Trust, UK.
  • Micali N; Great Ormond Street Institute of Child Health, University College London, UK; Department of Psychiatry, Faculty of Medicine, University of Geneva, Switzerland; and Department of Paediatrics Gynaecology and Obstetrics, Faculty of Medicine, University of Geneva, Switzerland.
  • Reichenberg A; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Hickman M; Population Health Sciences, Bristol Medical School, University of Bristol, UK.
  • Rai D; Population Health Sciences, Bristol Medical School, University of Bristol, UK; National Institute of Health Research Biomedical Research Centre, University of Bristol, UK; and Avon and Wiltshire Mental Health Partnership NHS Trust, UK.
  • Haworth S; 1MRC Integrative Epidemiology Unit, University of Bristol, UK; and Population Health Sciences, Bristol Medical School, University of Bristol, UK.
  • Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, UK; and Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, UK.
  • Altschul D; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, UK.
  • Flaig R; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, UK; and Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, UK.
  • McIntosh AM; Division of Psychiatry, University of Edinburgh, UK.
  • Lawlor DA; MRC Integrative Epidemiology Unit at the University of Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, UK; and National Institute of Health Research Biomedical Research Centre, University of Bristol, UK.
  • Porteous D; Centre for Genomic and Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, UK.
  • Timpson NJ; MRC Integrative Epidemiology Unit at the University of Bristol, UK; and Population Health Sciences, Bristol Medical School, University of Bristol, UK.
Br J Psychiatry ; 218(6): 334-343, 2021 06.
Article in English | MEDLINE | ID: covidwho-1067367
ABSTRACT

BACKGROUND:

The COVID-19 pandemic and mitigation measures are likely to have a marked effect on mental health. It is important to use longitudinal data to improve inferences.

AIMS:

To quantify the prevalence of depression, anxiety and mental well-being before and during the COVID-19 pandemic. Also, to identify groups at risk of depression and/or anxiety during the pandemic.

METHOD:

Data were from the Avon Longitudinal Study of Parents and Children (ALSPAC) index generation (n = 2850, mean age 28 years) and parent generation (n = 3720, mean age 59 years), and Generation Scotland (n = 4233, mean age 59 years). Depression was measured with the Short Mood and Feelings Questionnaire in ALSPAC and the Patient Health Questionnaire-9 in Generation Scotland. Anxiety and mental well-being were measured with the Generalised Anxiety Disorder Assessment-7 and the Short Warwick Edinburgh Mental Wellbeing Scale.

RESULTS:

Depression during the pandemic was similar to pre-pandemic levels in the ALSPAC index generation, but those experiencing anxiety had almost doubled, at 24% (95% CI 23-26%) compared with a pre-pandemic level of 13% (95% CI 12-14%). In both studies, anxiety and depression during the pandemic was greater in younger members, women, those with pre-existing mental/physical health conditions and individuals in socioeconomic adversity, even when controlling for pre-pandemic anxiety and depression.

CONCLUSIONS:

These results provide evidence for increased anxiety in young people that is coincident with the pandemic. Specific groups are at elevated risk of depression and anxiety during the COVID-19 pandemic. This is important for planning current mental health provisions and for long-term impact beyond this pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Child / Female / Humans / Middle aged Country/Region as subject: Europa Language: English Journal: Br J Psychiatry Year: 2021 Document Type: Article Affiliation country: Bjp.2020.242

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Adult / Child / Female / Humans / Middle aged Country/Region as subject: Europa Language: English Journal: Br J Psychiatry Year: 2021 Document Type: Article Affiliation country: Bjp.2020.242