COVID-19 lessons from the dish: Dissecting CNS manifestations through brain organoids.
EMBO J
; 40(2): e107213, 2021 01 15.
Article
in English
| MEDLINE | ID: covidwho-1068058
ABSTRACT
COVID-19 is increasingly understood as a systemic disease with pathogenic manifestations beyond the respiratory tract. Recent work by Ramani et al (2020) dissects the cellular and molecular mechanisms of SARS-CoV-2's neurotrophic properties, using viral exposure of human brain organoids. Their findings highlight neurons as primary target of cerebral SARS-CoV-2 infection and uncover its Tau-related neurotoxicity.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Brain
/
Organoids
/
Tau Proteins
/
COVID-19
Limits:
Humans
Language:
English
Journal:
EMBO J
Year:
2021
Document Type:
Article
Affiliation country:
Embj.2020107213
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