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Real-World Inpatient Use of Medications Repurposed for Coronavirus Disease 2019 in United States Hospitals, March-May 2020.
Kadri, Sameer S; Demirkale, Cumhur Y; Sun, Junfeng; Busch, Lindsay M; Strich, Jeffrey R; Rosenthal, Ning; Warner, Sarah.
  • Kadri SS; Critical Care Medicine Department, NIH Clinical Center, Bethesda, Maryland, USA.
  • Demirkale CY; Critical Care Medicine Department, NIH Clinical Center, Bethesda, Maryland, USA.
  • Sun J; Critical Care Medicine Department, NIH Clinical Center, Bethesda, Maryland, USA.
  • Busch LM; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Strich JR; Critical Care Medicine Department, NIH Clinical Center, Bethesda, Maryland, USA.
  • Rosenthal N; Premier Inc., Charlotte, North Carolina, USA.
  • Warner S; Critical Care Medicine Department, NIH Clinical Center, Bethesda, Maryland, USA.
Open Forum Infect Dis ; 8(2): ofaa616, 2021 Feb.
Article in English | MEDLINE | ID: covidwho-1069291
ABSTRACT
We report off-label use patterns for medications repurposed for coronavirus disease 2019 (COVID-19) at 318 US hospitals. Inpatient hydroxychloroquine use declined by 80%, whereas corticosteroids and tocilizumab were initiated 2 days earlier in May versus March 2020. Two thirds of ventilated COVID-19 patients were already receiving corticosteroids during March-May 2020, resembling pre-COVID use in mechanically ventilated influenza patients.
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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Open Forum Infect Dis Year: 2021 Document Type: Article Affiliation country: Ofid

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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Open Forum Infect Dis Year: 2021 Document Type: Article Affiliation country: Ofid