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Neurological involvement of COVID-19: from neuroinvasion and neuroimmune crosstalk to long-term consequences.
Septyaningtrias, Dian Eurike; Susilowati, Rina.
  • Septyaningtrias DE; Department of Histology and Cell Biology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Jalan Farmako Sekip Utara, Yogyakarta55281, Indonesia.
  • Susilowati R; Department of Histology and Cell Biology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Jalan Farmako Sekip Utara, Yogyakarta55281, Indonesia.
Rev Neurosci ; 32(4): 427-442, 2021 06 25.
Article in English | MEDLINE | ID: covidwho-1069660
Semantic information from SemMedBD (by NLM)
1. Virus Diseases CAUSES Coronavirus Infections
Subject
Virus Diseases
Predicate
CAUSES
Object
Coronavirus Infections
2. Virus Diseases CAUSES Coronavirus Infections
Subject
Virus Diseases
Predicate
CAUSES
Object
Coronavirus Infections
ABSTRACT
As the coronavirus disease 2019 (COVID-19) pandemic continues to be a multidimensional threat to humanity, more evidence of neurological involvement associated with it has emerged. Neuroimmune interaction may prove to be important not only in the pathogenesis of neurological manifestations but also to prevent systemic hyperinflammation. In this review, we summarize reports of COVID-19 cases with neurological involvement, followed by discussion of possible routes of entry, immune responses against coronavirus infection in the central nervous system and mechanisms of nerve degeneration due to viral infection and immune responses. Possible mechanisms for neuroprotection and virus-associated neurological consequences are also discussed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Central Nervous System / SARS-CoV-2 / COVID-19 / Nervous System Diseases Topics: Long Covid Limits: Humans Language: English Journal: Rev Neurosci Journal subject: Neurology Year: 2021 Document Type: Article Affiliation country: Revneuro-2020-0092

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Central Nervous System / SARS-CoV-2 / COVID-19 / Nervous System Diseases Topics: Long Covid Limits: Humans Language: English Journal: Rev Neurosci Journal subject: Neurology Year: 2021 Document Type: Article Affiliation country: Revneuro-2020-0092