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Therapeutic approaches to coronavirus infection according to "One Health" concept.
Rossi, Giacomo; Galosi, Livio; Gavazza, Alessandra; Cerquetella, Matteo; Mangiaterra, Sara.
  • Rossi G; School of Biosciences and Veterinary Medicine, University of Camerino, Italy. Electronic address: giacomo.rossi@unicam.it.
  • Galosi L; School of Biosciences and Veterinary Medicine, University of Camerino, Italy.
  • Gavazza A; School of Biosciences and Veterinary Medicine, University of Camerino, Italy.
  • Cerquetella M; School of Biosciences and Veterinary Medicine, University of Camerino, Italy.
  • Mangiaterra S; School of Biosciences and Veterinary Medicine, University of Camerino, Italy.
Res Vet Sci ; 136: 81-88, 2021 May.
Article in English | MEDLINE | ID: covidwho-1070578
ABSTRACT
Coronaviridae constantly infect human and animals causing respiratory, gastroenteric or systemic diseases. Over time, these viruses have shown a marked ability to mutate, jumping over the human-animal barrier, thus becoming from enzootic to zoonotic. In the last years, numerous therapeutic protocols have been developed, mainly for severe acute respiratory syndromes in humans. The aim of this review is to summarize drugs or other approaches used in coronavirus infections focusing on different roles of these molecules or bacterial products on viral adhesion and replication or in modulating the host's immune system. Within the "One Health" concept, the study of viral pathogenic role and possible therapeutic approaches in both humans and animals is essential to protect public health.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Coronavirus Infections Limits: Animals / Humans Language: English Journal: Res Vet Sci Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Coronavirus Infections Limits: Animals / Humans Language: English Journal: Res Vet Sci Year: 2021 Document Type: Article