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Aspects of Point-of-Care Diagnostics for Personalized Health Wellness.
Kumar, Sandeep; Nehra, Monika; Khurana, Sakina; Dilbaghi, Neeraj; Kumar, Vanish; Kaushik, Ajeet; Kim, Ki-Hyun.
  • Kumar S; Department of Bio and Nano Technology, Guru Jambheshwar University of Science and Technology, Hisar, Haryana 125001, India.
  • Nehra M; Department of Bio and Nano Technology, Guru Jambheshwar University of Science and Technology, Hisar, Haryana 125001, India.
  • Khurana S; Department of Bio and Nano Technology, Guru Jambheshwar University of Science and Technology, Hisar, Haryana 125001, India.
  • Dilbaghi N; Department of Bio and Nano Technology, Guru Jambheshwar University of Science and Technology, Hisar, Haryana 125001, India.
  • Kumar V; National Agri-Food Biotechnology Institute (NABI), Mohali, Punjab, India.
  • Kaushik A; NanoBioTech Laboratory, Department of Natural Sciences, Division of Sciences, Art, & Mathematics, Florida Polytechnic University, Lakeland, FL, 33805-8531, USA.
  • Kim KH; Department of Civil & Environmental Engineering, Hanyang University, Seoul 04763, Republic of Korea.
Int J Nanomedicine ; 16: 383-402, 2021.
Article in English | MEDLINE | ID: covidwho-1076350
Semantic information from SemMedBD (by NLM)
1. Operative Surgical Procedures TREATS Severe disease
Subject
Operative Surgical Procedures
Predicate
TREATS
Object
Severe disease
2. Challenge TREATS Communicable Diseases
Subject
Challenge
Predicate
TREATS
Object
Communicable Diseases
3. Operative Surgical Procedures TREATS Severe disease
Subject
Operative Surgical Procedures
Predicate
TREATS
Object
Severe disease
4. Challenge TREATS Communicable Diseases
Subject
Challenge
Predicate
TREATS
Object
Communicable Diseases
ABSTRACT
Advancements in analytical diagnostic systems for point-of-care (POC) application have gained considerable attention because of their rapid operation at the site required to manage severe diseases, even in a personalized manner. The POC diagnostic devices offer easy operation, fast analytical outcome, and affordable cost, which promote their advanced research and versatile adoptability. Keeping advantages in view, considerable efforts are being made to design and develop smart sensing components such as miniaturized transduction, interdigitated electrodes-based sensing chips, selective detection at low level, portable packaging, and sustainable durability to promote POC diagnostics according to the needs of patient care. Such effective diagnostics systems are in demand, which creates the challenge to make them more efficient in every aspect to generate a desired bio-informatic needed for better health access and management. Keeping advantages and scope in view, this mini review focuses on practical scenarios associated with miniaturized analytical diagnostic devices at POC application for targeted disease diagnostics smartly and efficiently. Moreover, advancements in technologies, such as smartphone-based operation, paper-based sensing assays, and lab-on-a-chip (LOC) which made POC more sensitive, informative, and suitable for major infectious disease diagnosis, are the main focus here. Besides, POC diagnostics based on automated patient sample integration with a sensing platform is continuously improving therapeutics interventions against specific infectious disease. This review also discussed challenges associated with state-of-the-art technology along with future research opportunities to design and develop next generation POC diagnostic systems needed to manage infectious diseases in a personalized manner.
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Keywords

Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Precision Medicine / Point-of-Care Testing Subject: Precision Medicine / Point-of-Care Testing Type of study: Diagnostic study / Prognostic study Language: English Journal: Int J Nanomedicine Clinical aspect: Prediction / Prognosis Year: 2021

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Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Precision Medicine / Point-of-Care Testing Subject: Precision Medicine / Point-of-Care Testing Type of study: Diagnostic study / Prognostic study Language: English Journal: Int J Nanomedicine Clinical aspect: Prediction / Prognosis Year: 2021
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