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Clinical and laboratory characteristics in outpatient diagnosis of COVID-19 in healthcare professionals in Rio de Janeiro, Brazil.
Porto, Luis Cristovao; Costa, Claudia H; Nunes, Alessandra S; Bouzas, Isabel; Ferreira, Tiago F; Porto, Vinicius M; Secco, Danielle A; Vilas Boas, Sandra; Faria, Anamelia Costa; Rufino, Rogerio.
  • Porto LC; Histocompatibility and Cryopreservation Laboratory, Institute of Biology Roberto Alcantara Gomes, UERJ, Rio de Janeiro, Brazil lcporto@uerj.br.
  • Costa CH; Clinical Pathology Service, Polyclinic Piquet Carneiro, UERJ, Rio de Janeiro, Brazil.
  • Nunes AS; Department of Pulmonology and Tisiology, Faculty of Medical Sciences and Service of Pulmonology, Polyclinic Piquet Carneiro, UERJ, Rio de Janeiro, Brazil.
  • Bouzas I; Medical Surgical Nursing Department, Nursing Faculty, Polyclinic Piquet Carneiro, UERJ, Rio de Janeiro, Brazil.
  • Ferreira TF; Health Research Support Facility Center (CAPCS), Polyclinic Piquet Carneiro, UERJ, Rio de Janeiro, Brazil.
  • Porto VM; Infectology Service, Polyclinic Piquet Carneiro, UERJ, Rio de Janeiro, Brazil.
  • Secco DA; Clinical Pathology Service, Polyclinic Piquet Carneiro, UERJ, Rio de Janeiro, Brazil.
  • Vilas Boas S; Histocompatibility and Cryopreservation Laboratory, Institute of Biology Roberto Alcantara Gomes, UERJ, Rio de Janeiro, Brazil.
  • Faria AC; Clinical Pathology Service, Polyclinic Piquet Carneiro, UERJ, Rio de Janeiro, Brazil.
  • Rufino R; Department of Pulmonology and Tisiology, Faculty of Medical Sciences and Service of Pulmonology, Polyclinic Piquet Carneiro, UERJ, Rio de Janeiro, Brazil.
J Clin Pathol ; 75(3): 185-192, 2022 Mar.
Article in English | MEDLINE | ID: covidwho-1079079
Preprint
This scientific journal article is probably based on a previously available preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
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ABSTRACT

AIMS:

This study aimed to identify the symptoms associated with early stage SARS-CoV-2 (COVID-19) infections in healthcare professionals (HCPs) using both clinical and laboratory data.

METHODS:

A total of 1297 patients, admitted between 18 March and 8 April 2020, were stratified according to their risk of developing COVID-19 using their responses to a questionnaire designed to evaluate symptoms and risk conditions.

RESULTS:

Anosmia/hyposmia (p<0.0001), fever (p<0.0001), body pain (p<0.0001) and chills (p=0.001) were all independent predictors for COVID-19, with a 72% estimated probability for detecting COVID-19 in nasopharyngeal swab samples. Leucopenia, relative monocytosis, decreased eosinophil values, C reactive protein (CRP) and platelets were also shown to be significant independent predictors for COVID-19.

CONCLUSIONS:

The significant clinical features for COVID-19 were identified as anosmia, fever, chills and body pain. Elevated CRP, leucocytes under 5400×109/L and relative monocytosis (>9%) were common among patients with a confirmed COVID-19 diagnosis. These variables may help, in the absence of reverse transcriptase PCR tests, to identify possible COVID-19 infections during pandemic outbreaks.

SUMMARY:

From 19 March to 8 April 2020, 1297 patients attended the Polyclinic Piquet Carneiro for COVID-19 detection. HCP data were analysed, and significant clinical features were anosmia, fever, chills and body pain. Elevated CRP, leucopenia and monocytosis were common in COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: South America / Brazil Language: English Journal: J Clin Pathol Year: 2022 Document Type: Article Affiliation country: Jclinpath-2020-206797

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: South America / Brazil Language: English Journal: J Clin Pathol Year: 2022 Document Type: Article Affiliation country: Jclinpath-2020-206797