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[SARS-CoV-2 and neurological disorders: the revelance of biomarkers?] / SARS-CoV-2 et atteintes neurologiques : quelle est la place des biomarqueurs ?
Bigot-Corbel, Edith; Lanore, Aymeric; Raulet, Celia; Delorme, Cécile; Azulay, Jean-Philippe; Lehmann, Sylvain; Beaudeux, Jean-Louis; Beauvieux, Marie-Christine; Sapin, Vincent; Peoc'h, Katell; Rucheton, Benoit.
  • Bigot-Corbel E; Laboratoire de biochimie, CHU de Nantes, Hôpital Laënnec, Saint-Herblain, France.
  • Lanore A; Département de Neurologie, APHP, Sorbonne-Université, Hôpital Pitié-Salpêtrière, Paris, France.
  • Raulet C; Service de biochimie, APHP, Hôpital Bichat, Paris, France.
  • Delorme C; Département de Neurologie, APHP, Sorbonne-Université, Hôpital Pitié-Salpêtrière, Paris, France, Sorbonne Université, Paris Brain Institute - ICM, Inserm U1127, CNRS UMR 7225, Paris, France.
  • Azulay JP; Service de neurologie et pathologie du mouvement, Centre expert Parkinson, Centre de compétences « Maladies rares du mouvement et de la cognition ¼, Hôpital de la Timone, Marseille, France ; vice-Président de la SFN.
  • Lehmann S; Institut de médecine régénératrice et de biothérapies (IRMB), Laboratoire de biochimie-protéomique clinique, CCBHM, Hôpital Saint-Éloi, CHU, Montpellier, France, Faculté de médecine, Université de Montpellier, France, Inserm U1040, Montpellier, France.
  • Beaudeux JL; Service de biochimie générale, Hôpital Necker-Enfants-malades, APHP, Paris, France.
  • Beauvieux MC; Service de biochimie, CHU de Bordeaux, Bordeaux, France, UM5536 CNRS-Université Bordeaux, Bordeaux, France.
  • Sapin V; Service de biochimie et génétique moléculaire, CHU, Clermont-Ferrand, France.
  • Peoc'h K; Service de biochimie, APHP, Hôpital Bichat, Paris, France, Université de Paris, UFR de médecine Xavier-Bichat, Paris, France.
  • Rucheton B; DMU BioGeM, Service de biochimie métabolique, APHP, Sorbonne Université, Hôpitaux universitaires Pitié-Salpêtrière, Paris, France.
Ann Biol Clin (Paris) ; 79(1): 7-16, 2021 02 01.
Article in French | MEDLINE | ID: covidwho-1079401
ABSTRACT
Soon after the pandemic, numerous publications described cases of neurological disorders associated with the SARS-CoV-2 infection. The range of neurological symptoms is becoming increasingly more extensive as the pandemic progresses. However, it is not yet well established whether the manifestations are due to direct viral damage to the nervous system or indirect consequences of the infection. This review presents an inventory of the biochemical markers studied in the context of neurological disorders related to SARS-CoV-2. By reflecting various physiopathological mechanisms, these biomarkers allow both a better understanding of the pathophysiology of Covid-19 and a contribution to the diagnosis of neurologic troubles; they could participate in the prognostic evaluation of patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Biomarkers / SARS-CoV-2 / COVID-19 / Nervous System Diseases Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: French Journal: Ann Biol Clin (Paris) Year: 2021 Document Type: Article Affiliation country: Abc.2021.1622

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Biomarkers / SARS-CoV-2 / COVID-19 / Nervous System Diseases Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: French Journal: Ann Biol Clin (Paris) Year: 2021 Document Type: Article Affiliation country: Abc.2021.1622