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Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?
Dubourg, Grégory; Lagier, Jean-Christophe; Brouqui, Philippe; Casalta, Jean-Paul; Jacomo, Véronique; La Scola, Bernard; Rolain, Jean-Marc; Raoult, Didier.
  • Dubourg G; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ., IRD, AP-HM, MEPHI, Marseille, France.
  • Lagier JC; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ., IRD, AP-HM, MEPHI, Marseille, France.
  • Brouqui P; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ., IRD, AP-HM, MEPHI, Marseille, France.
  • Casalta JP; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ., IRD, AP-HM, MEPHI, Marseille, France.
  • Jacomo V; Eurofins Biomnis, Lyon, France.
  • La Scola B; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ., IRD, AP-HM, MEPHI, Marseille, France.
  • Rolain JM; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ., IRD, AP-HM, MEPHI, Marseille, France. Electronic address: jean-marc.rolain@univ-amu.fr.
  • Raoult D; IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ., IRD, AP-HM, MEPHI, Marseille, France. Electronic address: didier.raoult@gmail.com.
J Microbiol Immunol Infect ; 54(5): 997-1000, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1081399
ABSTRACT
Among 275 patients with COVID-19, we found that median blood zinc level was significantly lower in patients with poor clinical outcome (N = 75) as compared to patients with good clinical outcome (N = 200) (840 µg/L versus 970 µg/L; p < 0.0001), suggesting that zinc supplementation could be useful for patients with severe COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Zinc / Dietary Supplements / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Prognostic study Topics: Traditional medicine Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged / Young adult Language: English Journal: J Microbiol Immunol Infect Journal subject: Allergy and Immunology / Microbiology Year: 2021 Document Type: Article Affiliation country: J.jmii.2021.01.012

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Zinc / Dietary Supplements / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Prognostic study Topics: Traditional medicine Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged / Young adult Language: English Journal: J Microbiol Immunol Infect Journal subject: Allergy and Immunology / Microbiology Year: 2021 Document Type: Article Affiliation country: J.jmii.2021.01.012