Sex differences in patients with covid-19: A retrospective cohort study and meta-analysis
Open Access Macedonian Journal of Medical Sciences
; 8(T1):574-597, 2020.
Article
in English
| Scopus | ID: covidwho-1082569
ABSTRACT
BACKGROUND:
Accumulated evidence revealed that male was much more likely to higher severity and fatality by SARS-CoV-2 infection than female patients, but few studies and meta-analyses have evaluated the sex differences of the infection and progression of COVID-19 patients.AIM:
We aimed to compare the sex differences of the epidemiological and clinical characteristics in COVID-19 patients;and to perform a meta-analysis evaluating the severe rate, fatality rate, and the sex differences of the infection and disease progression in COVID-19 patients.METHODS:
We analyzed clinical data of patients in Changchun Infectious Hospital and Center, Changchun, Northeast China;and searched PubMed, Embase, Web of Science, and Cochrane Library without any language restrictions for published articles that reported the data of sex-disaggregated, number of severe, and death patients on the confirmed diagnosis of adult COVID-19 patients.RESULTS:
The pooled severe rate and fatality rate of COVID-19 were 22.7% and 10.7%. Male incidence in the retrospective study was 58.1%, and the pooled incidence in male was 54.7%.CONCLUSION:
The pooled severe rate in male and female of COVID-19 was 28.2% and 18.8%, the risky of severe and death was about 1.6folds higher in male compared with female, especially for older patients (> 50 y). © 2020 Zhijun Li, Lina Feng, Wenyu Cui, Jian Zhang, Yingxin Huang, Yunhong Zhao, Fei Teng, Donglin Wu, Bonan Cao, Hui Wang, Liquan Deng, Qiong Yu.
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Type of study:
Cohort study
/
Observational study
/
Prognostic study
/
Reviews
Language:
English
Journal:
Open Access Macedonian Journal of Medical Sciences
Year:
2020
Document Type:
Article
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