Sinus Bradycardia Associated with Remdesivir Treatment in COVID-19: A Case Report and Literature Review.
J Cardiovasc Dev Dis
; 8(2)2021 Feb 12.
Article
in English
| MEDLINE | ID: covidwho-1085069
ABSTRACT
BACKGROUND:
Although remdesivir treatment is widely used during the pandemic coronavirus disease 2019 (COVID-19), there is scarce evidence regarding its cardiac side effects. CASE PRESENTATION We report the case of a 36-year-old male hospitalized due to severe COVID-19 symptoms. He presented with a 10-day history of fever (up to 39.7 °C), productive cough, hemoptysis, fatigue, myalgias and hypoxemia. The patient received supplemental oxygen, dexamethasone, remdesivir and empirical antibiotic treatment according to protocol. Asymptomatic sinus bradycardia developed on hospital day 3 (namely, heart rate 39/min compared to 92/min on admission). Secondary causes of bradycardia were excluded based on the absence of relevant evidence from laboratory work-up and echocardiographic examination. The patient's rhythm restored to normal 9 days after the discontinuation of remdesivir.CONCLUSIONS:
Considering the frequent use of remdesivir in patients with COVID-19, physicians should be aware of this possible adverse event.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Case report
/
Prognostic study
/
Reviews
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
Jcdd8020018
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