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Impact of a long-term air pollution exposure on the case fatality rate of COVID-19 patients-A multicity study.
Hou, Chang-Kai; Qin, Ya-Fei; Wang, Grace; Liu, Quan-Lei; Yang, Xin-Yu; Wang, Hao.
  • Hou CK; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
  • Qin YF; Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, China.
  • Wang G; Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Liu QL; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
  • Yang XY; Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
  • Wang H; Department of General Surgery, Tianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, China.
J Med Virol ; 93(5): 2938-2946, 2021 05.
Article in English | MEDLINE | ID: covidwho-1196525
ABSTRACT
Evidence in the literature suggests that air pollution exposure affects outcomes of patients with COVID-19. However, the extent of this effect requires further investigation. This study was designed to investigate the relationship between long-term exposure to air pollution and the case fatality rate (CFR) of patients with COVID-19. The data on air quality index (AQI), PM2.5, PM10, SO2 , NO2 , and O3 from 14 major cities in China in the past 5 years (2015-2020) were collected, and the CRF of COVID-19 patients in these cities was calculated. First, we investigated the correlation between CFR and long-term air quality indicators. Second, we examined the air pollutants affecting CFR and evaluated their predictive values. We found a positive correlation between the CFR and AQI (1, 3, and 5 years), PM2.5 (1, 3, and 5 years), and PM10 (1, 3, and 5 years). Further analysis indicated the more significant correlation for both AQI (3 and 5 years) and PM2.5 (1, 3, and 5 years) with CFR, and moderate predictive values for air pollution indicators such as AQI (1, 3, and 5 years) and PM2.5 (1, 3, and 5 years) for CFR. Our results indicate that long-term exposure to severe air pollution is associated with higher CFR of COVID-19 patients. Air pollutants such as PM2.5 may assist with the prediction of CFR for COVID-19 patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Inhalation Exposure / Air Pollution / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2021 Document Type: Article Affiliation country: Jmv.26807

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Inhalation Exposure / Air Pollution / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2021 Document Type: Article Affiliation country: Jmv.26807