Purposing Saikosaponins for the treatment of COVID-19.

Bahbah, Eshak I; Negida, Ahmed; Nabet, Mohamed Salah

Bahbah, Eshak I; Negida, Ahmed; Nabet, Mohamed Salah.

Bahbah EI; School of Medicine, Al-Azhar University, Damietta, Egypt.
Negida A; School of Pharmacy and Biological Sciences, University of Portsmouth, UK.
Nabet MS; School of Medicine, Zagazig University, Sharkia, Egypt.

Med Hypotheses ; 140: 109782, 2020 07.

Article in English | MEDLINE | ID: covidwho-108760

Subject(s)

Anti-Inflammatory Agents/therapeutic use; Antiviral Agents/therapeutic use; Betacoronavirus/drug effects; Coronavirus Infections/drug therapy; Drug Repositioning; Immunologic Factors/therapeutic use; Oleanolic Acid/analogs & derivatives; Pandemics; Pneumonia, Viral/drug therapy; Saponins/therapeutic use; Angiotensin-Converting Enzyme 2; Anti-Inflammatory Agents/pharmacology; Antiviral Agents/pharmacology; COVID-19; Coronavirus Infections/complications; Cytokine Release Syndrome/drug therapy; Cytokine Release Syndrome/etiology; Humans; Immunologic Factors/pharmacology; Lymphocyte Activation/drug effects; Molecular Docking Simulation; Oleanolic Acid/pharmacology; Oleanolic Acid/therapeutic use; Peptidyl-Dipeptidase A/drug effects; Pneumonia, Viral/complications; Receptors, Virus/drug effects; SARS-CoV-2; Saponins/pharmacology; COVID-19 Drug Treatment

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Oleanolic Acid / Antiviral Agents / Pneumonia, Viral / Saponins / Coronavirus Infections / Drug Repositioning / Pandemics / Betacoronavirus / Immunologic Factors / Anti-Inflammatory Agents Topics: Long Covid Limits: Humans Language: English Journal: Med Hypotheses Year: 2020 Document Type: Article Affiliation country: J.mehy.2020.109782

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