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Characteristics of headache attributed to COVID-19 infection and predictors of its frequency and intensity: A cross sectional study.
Magdy, Rehab; Hussein, Mona; Ragaie, Christine; Abdel-Hamid, Hoda M; Khallaf, Ahmed; Rizk, Hoda I; Dahshan, Ahmed.
  • Magdy R; Department of Neurology, Cairo University, Cairo, Egypt.
  • Hussein M; Department of Neurology, Beni-Suef University, Beni-Suef, Egypt.
  • Ragaie C; Department of Neurology, Cairo University, Cairo, Egypt.
  • Abdel-Hamid HM; Department of Neurology, Cairo University, Cairo, Egypt.
  • Khallaf A; Department of Neurology, Beni-Suef University, Beni-Suef, Egypt.
  • Rizk HI; Public Health and Community Medicine, Cairo University, Cairo, Egypt.
  • Dahshan A; Department of Neurology, Cairo University, Cairo, Egypt.
Cephalalgia ; 40(13): 1422-1431, 2020 11.
Article in English | MEDLINE | ID: covidwho-1088414
ABSTRACT

OBJECTIVE:

To study the characteristics of headache attributed to COVID-19 infection and predictors of its severity.

METHODS:

A cross-sectional study involved 172 individuals who had headache due to COVID-19 infection. A detailed analysis of such headache was done through a face-to-face interview. Patients with any other form of secondary headache were excluded. Labs, including lymphocytic count, C-reactive protein, D-dimer and ferritin and chest imaging, were made available.

RESULTS:

THE majority of our patients had a diffuse headache (52.9%). It was pressing in 40.7%, with median intensity of 7 (assessed by visual analogue scale) and median frequency of 7 days/week. Patients with preexisting primary headache (52.9%) had significantly more frequent COVID-19 related headache than those without (47.1%) (p = 0.001). Dehydrated patients (64.5%) had more frequent COVID-19 related headache than those who were not dehydrated (35.5%) (p = 0.029). Patients with fever (69.8%) had significantly higher frequency and intensity of COVID-19 related headache compared to those without fever (30.2%) (p = 0.003, 0.012). Patients with comorbidities (19.8%) had significantly higher frequency and intensity of headache than those without comorbidities (80.2%) (p = 0.006, 0.003). After multiple linear regression, primary headache disorders, dehydration and comorbidities were considered predictors of frequency of COVID-19 related headache. Meanwhile, fever and dehydration were predictors of pain intensity.

CONCLUSION:

Healthcare providers of COVID-19 patients need to be aware of frequency and intensity predictors of COVID-19 related headache Primary headache disorders, fever, dehydration, and comorbidities.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Headache Type of study: Observational study / Prognostic study / Qualitative research / Randomized controlled trials Topics: Long Covid Limits: Adult / Female / Humans / Male Language: English Journal: Cephalalgia Year: 2020 Document Type: Article Affiliation country: 0333102420965140

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Headache Type of study: Observational study / Prognostic study / Qualitative research / Randomized controlled trials Topics: Long Covid Limits: Adult / Female / Humans / Male Language: English Journal: Cephalalgia Year: 2020 Document Type: Article Affiliation country: 0333102420965140