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COVID-19-from mucosal immunology to IBD patients.
Weidinger, Carl; Hegazy, Ahmed Nabil; Glauben, Rainer; Siegmund, Britta.
  • Weidinger C; Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany.
  • Hegazy AN; Clinician Scientist Program, Berlin Institute of Health, Berlin, Germany.
  • Glauben R; Department for Medicine (Gastroenterology, Infectious diseases, Rheumatology), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany.
  • Siegmund B; Clinician Scientist Program, Berlin Institute of Health, Berlin, Germany.
Mucosal Immunol ; 14(3): 566-573, 2021 05.
Article in English | MEDLINE | ID: covidwho-1091501
ABSTRACT
Viral infections with SARS-CoV-2 can cause a multi-facetted disease, which is not only characterized by pneumonia and overwhelming systemic inflammatory immune responses, but which can also directly affect the digestive system and infect intestinal epithelial cells. Here, we review the current understanding of intestinal tropism of SARS-CoV-2 infection, its impact on mucosal function and immunology and summarize the effect of immune-suppression in patients with inflammatory bowel disease (IBD) on disease outcome of COVID-19 and discuss IBD-relevant implications for the clinical management of SARS-CoV-2 infected individuals.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Inflammatory Bowel Diseases / Immunity, Mucosal / Host-Pathogen Interactions / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Mucosal Immunol Journal subject: Allergy and Immunology Year: 2021 Document Type: Article Affiliation country: S41385-021-00384-9

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Inflammatory Bowel Diseases / Immunity, Mucosal / Host-Pathogen Interactions / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Mucosal Immunol Journal subject: Allergy and Immunology Year: 2021 Document Type: Article Affiliation country: S41385-021-00384-9