Conventional and Nanotechnology-Based Sensing Methods for SARS Coronavirus (2019-nCoV).
ACS Appl Bio Mater
; 4(2): 1178-1190, 2021 02 15.
Article
in English
| MEDLINE | ID: covidwho-1091529
ABSTRACT
Ongoing pandemic coronavirus (COVID-19) has affected over 218 countries and infected 88,512,243 and 1,906,853 deaths reported by Jan. 8, 2021. At present, vaccines are being developed in Europe, Russia, USA, and China, although some of these are in phase III of trials, which are waiting to be available for the general public. The only option available now is by vigorous testing, isolation of the infected cases, and maintaining physical and social distances. Numerous methods are now available or being developed for testing the suspected cases, which may act as carriers of the virus. In this review, efforts have been made to discuss the conventional as well as fast, rapid, and efficient testing methods developed for the diagnosis of 2019-nCoV.Testing methods can be based on the sensing of targets, which include RNA, spike proteins and antibodies such as IgG and IgM. Apart from the development of RNA targeted PCR, antibody and VSV pseudovirus neutralization assay along with several other diagnostic techniques have been developed. Additionally, nanotechnology-based sensors are being developed for the diagnosis of the virus, and these are also discussed.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Biosensing Techniques
/
Spike Glycoprotein, Coronavirus
/
SARS-CoV-2
/
COVID-19
Type of study:
Diagnostic study
Topics:
Vaccines
Limits:
Animals
/
Humans
Language:
English
Journal:
ACS Appl Bio Mater
Year:
2021
Document Type:
Article
Affiliation country:
Acsabm.0c01545
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