Evaluation of hematological parameters in covid-19 infected patients

ABSTRACT

Aims & Objectives: The present study was undertaken to evaluate prognostic relevance of hematological parameters in COVID-19 infected patients for early identification of critical patients for early management. Patients/Materials & Methods: A retrospective study was conducted over a period of 2 months (01st July 2020 to 1st September 2020) on 912 admitted COVID-19 positive patients. 2 ml venous blood was aseptically collected in EDTA vaccutainer and processed in automated hematology analyser (ADVIA 2120i). Patients with hematological malignancy were excluded from the study. Patients were assigned into three groups according to the severity of disease (mild/asymptomatic, moderate and severe) as well as on the basis of clinical outcome (discharged ordeath). Results: To talleucocyte count, absolute neutrophil count, neutrophillymphocyte ratio, plateletlymphocyte ratio, reddistribution width were significantly higher (p<0.05) is the decreased patients and in severe disease group where as hemoglobin and hematocr it was significant lower in these patients. Lymphopenia was recorded in decreased patient but was not statically significant. Discussion & Conclusion: COVID-19 patients with severe disease and poor outcome showed significant difference in ther outine hematological parameter such as total leucocyte count, absolute neutrophil count, absolute monocyte count, neutrophillymphocyte ratio, plateletlymphocyte ratio, reddistribution width and hematocrit which are readily available and can be helpful in the prediction of COVID-19 patien toutcome.