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Efficacy and Safety of New and Emerging Drugs for COVID-19: Favipiravir and Dexamethasone.
Sood, Shivani; Bhatia, Gurpreet Kaur; Seth, Prachi; Kumar, Pawan; Kaur, Jagjit; Gupta, Vidisha; Punia, Sandeep; Tuli, Hardeep Singh.
  • Sood S; Department of Biotechnology, Mukand Lal National College, Yamuna Nagar, India.
  • Bhatia GK; Department of Physics, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, 133207 India.
  • Seth P; Department of Biotechnology, Mukand Lal National College, Yamuna Nagar, India.
  • Kumar P; Institute of Plant Sciences, Agricultural Research Organisation (ARO), 7505101 Rishon LeZion, Israel.
  • Kaur J; Graduate School of Biomedical Engineering, ARC Centre of Excellence in Nanoscale Biophotonics (CNBP), Faculty of Engineering, The University of New South Wales, Sydney, 2052 Australia.
  • Gupta V; Department of Zoology, Mukand Lal National College, Yamuna Nagar, India.
  • Punia S; Department of Biotechnology, Multani Mal Modi College, Patiala, India.
  • Tuli HS; Department of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, 133207 India.
Curr Pharmacol Rep ; 7(2): 49-54, 2021.
Article in English | MEDLINE | ID: covidwho-1095761
ABSTRACT
PURPOSE OF REVIEW The widespread respiratory disease of virus known as severe acute respiratory syndrome-coronavirus 2019 (SAR-CoV-2) had infected more than 200 countries and caused pandemic and havoc in the world. RECENT

FINDINGS:

The genome of the virus was sequenced rapidly to study its mechanism, epidemiology, drugs, and vaccines. Many drugs and vaccines are being studied by researchers to treat and prevent the SARS-CoV-2. Favipiravir and dexamethasone are repurposed drugs which showed therapeutic potential and pharmaceutical efficacy against SARS-CoV-2.

SUMMARY:

The review describes the path of favipiravir and dexamethasone from chemistry to mechanisms of action to combat SARS-CoV-2. In addition, the potential side effects are also summarized to study their potential to control corona virus 2019.
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Full text: Available Collection: International databases Database: MEDLINE Topics: Vaccines Language: English Journal: Curr Pharmacol Rep Year: 2021 Document Type: Article Affiliation country: S40495-021-00253-w

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Full text: Available Collection: International databases Database: MEDLINE Topics: Vaccines Language: English Journal: Curr Pharmacol Rep Year: 2021 Document Type: Article Affiliation country: S40495-021-00253-w