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Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19.
Yao, Yao; Ye, Fei; Li, Kailong; Xu, Peng; Tan, Wenjie; Feng, Quansheng; Rao, Shuquan.
  • Yao Y; School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
  • Ye F; Division of Hematology/Oncology, Boston Children's Hospital, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Li K; NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control & Prevention, Chinese Center for Disease Control and Prevention, China CDC, Beijing, China.
  • Xu P; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Tan W; Hematology Center of Cyrus Tang Medical Institute, Soochow University, Suzhou, China.
  • Feng Q; NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control & Prevention, Chinese Center for Disease Control and Prevention, China CDC, Beijing, China.
  • Rao S; School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Signal Transduct Target Ther ; 6(1): 85, 2021 02 22.
Article in English | MEDLINE | ID: covidwho-1096318
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Membrane Transport Proteins / Chromosomes, Human, Pair 3 / Receptors, CCR / Genetic Loci / Gene Editing / Epigenome / SARS-CoV-2 / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2021 Document Type: Article Affiliation country: S41392-021-00519-1

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Membrane Transport Proteins / Chromosomes, Human, Pair 3 / Receptors, CCR / Genetic Loci / Gene Editing / Epigenome / SARS-CoV-2 / COVID-19 Type of study: Prognostic study Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2021 Document Type: Article Affiliation country: S41392-021-00519-1