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HIV infection and COVID-19: risk factors for severe disease.
Etienne, Nicolas; Karmochkine, Marina; Slama, Laurence; Pavie, Juliette; Batisse, Dominique; Usubillaga, Rafael; Letembet, Valerie-Anne; Brazille, Patricia; Canouï, Etienne; Slama, Dorsaf; Joumaa, Hassan; Canoui-Poitrine, Florence; Segaux, Lauriane; Weiss, Laurence; Viard, Jean-Paul; Salmon, Dominique.
  • Etienne N; Department of Immunology and Infectious Diseases, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Hôpitaux Universitaires Paris Centre - Université de Paris.
  • Karmochkine M; University of Paris School of Medicine.
  • Slama L; Department of Immunology and Infectious Diseases, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Hôpitaux Universitaires Paris Centre - Université de Paris.
  • Pavie J; Department of Immunology and Infectious Diseases, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Hôpitaux Universitaires Paris Centre - Université de Paris.
  • Batisse D; Department of Immunology and Infectious Diseases, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Hôpitaux Universitaires Paris Centre - Université de Paris.
  • Usubillaga R; Department of Immunology and Infectious Diseases, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Hôpitaux Universitaires Paris Centre - Université de Paris.
  • Letembet VA; Department of Immunology and Infectious Diseases, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Hôpitaux Universitaires Paris Centre - Université de Paris.
  • Brazille P; Department of Immunology and Infectious Diseases, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Hôpitaux Universitaires Paris Centre - Université de Paris.
  • Canouï E; Department of Immunology and Infectious Diseases, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Hôpitaux Universitaires Paris Centre - Université de Paris.
  • Slama D; University of Paris School of Medicine.
  • Joumaa H; Antimicrobial Stewardship Team, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Paris Centre-Site Cochin.
  • Canoui-Poitrine F; Department of Immunology and Infectious Diseases, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Hôpitaux Universitaires Paris Centre - Université de Paris.
  • Segaux L; Department of Pneumology, Cochin-Hôtel-Dieu Hospital, Assistance Publique -Hôpitaux de Paris (APHP), Paris.
  • Weiss L; Clinical Research Unit, Department of Public Health, Henri Mondor Hospital, AP-HP.
  • Viard JP; University Paris-Est Créteil (UPEC) School of Medicine.
  • Salmon D; INSERM U955, IMRB- CEpiA team, Henri Mondor Hospital, APHP, Créteil, France.
AIDS ; 34(12): 1771-1774, 2020 10 01.
Article in English | MEDLINE | ID: covidwho-1105050
ABSTRACT
We performed an observational prospective monocentric study in patients living with HIV (PLWH) diagnosed with COVID-19. Fifty-four PLWH developed COVID-19 with 14 severe (25.9%) and five critical cases (9.3%), respectively. By multivariate analysis, age, male sex, ethnic origin from sub-Saharan Africa and metabolic disorder were associated with severe or critical forms of COVID-19. Prior CD4 T cell counts did not differ between groups. No protective effect of a particular antiretroviral class was observed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / HIV Infections / Coronavirus Infections Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Africa / Europa Language: English Journal: AIDS Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / HIV Infections / Coronavirus Infections Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Africa / Europa Language: English Journal: AIDS Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2020 Document Type: Article