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Sex-based differences in severity and mortality in COVID-19.
Alwani, Mustafa; Yassin, Aksam; Al-Zoubi, Raed M; Aboumarzouk, Omar M; Nettleship, Joanne; Kelly, Daniel; Al-Qudimat, Ahmad R; Shabsigh, Ridwan.
  • Alwani M; Surgical Research Section, Hamad Medical Corporation, Doha, Qatar.
  • Yassin A; Jordan University of Science and Technology, School of Medicine, Irbid, Jordan.
  • Al-Zoubi RM; Surgical Research Section, Hamad Medical Corporation, Doha, Qatar.
  • Aboumarzouk OM; Department of Surgery, Hamad Medical Corporation, Division of Urology/Andrology & Men's Health, Doha, Qatar.
  • Nettleship J; Center of Medicine and Health Sciences, Dresden International University, Dresden, Germany.
  • Kelly D; Surgical Research Section, Hamad Medical Corporation, Doha, Qatar.
  • Al-Qudimat AR; Department of Chemistry, Jordan University of Science and Technology, Irbid, Jordan.
  • Shabsigh R; Department of Surgery, Hamad Medical Corporation, Doha, Qatar.
Rev Med Virol ; 31(6): e2223, 2021 11.
Article in English | MEDLINE | ID: covidwho-1107715
ABSTRACT
The current coronavirus disease (COVID-19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS-CoV and MERS-CoV, and viral infections in general. Here, we discuss the sex-disaggregated epidemiological data for COVID-19 and highlight underlying differences that may explain the sexual dimorphism to help inform risk stratification strategies and therapeutic options.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Sex Characteristics / Adaptive Immunity / SARS-CoV-2 / COVID-19 / Immunity, Innate Type of study: Prognostic study Topics: Vaccines Limits: Female / Humans / Male Language: English Journal: Rev Med Virol Journal subject: Virology Year: 2021 Document Type: Article Affiliation country: Rmv.2223

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Sex Characteristics / Adaptive Immunity / SARS-CoV-2 / COVID-19 / Immunity, Innate Type of study: Prognostic study Topics: Vaccines Limits: Female / Humans / Male Language: English Journal: Rev Med Virol Journal subject: Virology Year: 2021 Document Type: Article Affiliation country: Rmv.2223