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COVID-19 vaccines: what happened to evidence-based medicine?
Quek, Eleanor; Tahir, Hasan.
  • Quek E; Department of General Medicine, Barnet Hospital, Royal Free London NHS Foundation Trust, London, UK.
  • Tahir H; Department of Rheumatology and General Medicine, Barnet Hospital, Royal Free London NHS Foundation, London, UK.
Br J Hosp Med (Lond) ; 82(2): 1-4, 2021 Feb 02.
Article in English | MEDLINE | ID: covidwho-1110766
ABSTRACT
The UK government recently decided to extend the interval between the first dose of the Pfizer BioNTech and AstraZeneca COVID-19 vaccines from 3 weeks to 12 weeks to maximise the number of people receiving the initial dose, despite the trials only providing vaccine efficacy data based on a schedule of 21 days between doses. This editorial discusses whether there is evidence to support this policy change.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Vaccination Coverage / Immunogenicity, Vaccine / COVID-19 Vaccines / COVID-19 Type of study: Observational study Topics: Vaccines Limits: Humans Country/Region as subject: Europa Language: English Journal: Br J Hosp Med (Lond) Journal subject: Hospitals / Medicine Year: 2021 Document Type: Article Affiliation country: Hmed.2021.0047

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Vaccination Coverage / Immunogenicity, Vaccine / COVID-19 Vaccines / COVID-19 Type of study: Observational study Topics: Vaccines Limits: Humans Country/Region as subject: Europa Language: English Journal: Br J Hosp Med (Lond) Journal subject: Hospitals / Medicine Year: 2021 Document Type: Article Affiliation country: Hmed.2021.0047