Detection of SARS-coronavirus-2 in the central nervous system of patients with severe acute respiratory syndrome and seizures.
J Neurovirol
; 27(2): 348-353, 2021 04.
Article
in English
| MEDLINE | ID: covidwho-1111382
ABSTRACT
This study was designed to evaluate whether severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can directly target the central nervous system (CNS). We present four patients suffering from the loss of consciousness and seizure during the clinical course of COVID-19 infection. In addition to positive nasopharyngeal swab tests, SARS-CoV-2 has been detected in their cerebrospinal fluid. This report indicates the neuroinvasive potential of SARS-CoV-2, suggesting the ability of this virus to spread from the respiratory tract to the CNS.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Seizures
/
Cerebrospinal Fluid
/
Severe Acute Respiratory Syndrome
/
SARS-CoV-2
/
COVID-19
Type of study:
Case report
/
Experimental Studies
/
Prognostic study
Topics:
Long Covid
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
/
Young adult
Language:
English
Journal:
J Neurovirol
Journal subject:
Neurology
/
Virology
Year:
2021
Document Type:
Article
Affiliation country:
S13365-020-00938-w
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