Comparison of HRCT Chest and RT-PCR in Diagnosis of COVID-19.
J Coll Physicians Surg Pak
; 30(1): S1-S6, 2021 Jan.
Article
in English
| MEDLINE | ID: covidwho-1112938
ABSTRACT
OBJECTIVE:
To compare the diagnostic accuracies of HRCT chest and RT-PCR results in diagnosis of coronavirus disease (COVID-19) in a tertiary care hospital in Lahore. STUDYDESIGN:
Descriptive study. PLACE AND DURATION OF STUDY Department of Radiology and Central Research Lab, Lahore General Hospital, Lahore, from April to July, 2020.METHODOLOGY:
Patients aged 18 to 83 years, who had clinically suspected symptoms of COVID-19 (fever, cough/sore throat or shortness of breath) presenting in outpatient or emergency department, were included. These patients had their HRCT chest conducted from Radiology Department and RT-PCR performed at Central Research Lab. These data were retrieved from electronic system of PACS. Results were categorised into positive and negative findings for COVID-19. Diagnostic accuracies of HRCT chest and first RT-PCR along with 95% confidence interval were calculated.RESULTS:
A total of 94 patients, 55 (58.5%) males and 39 (41.5%) were females. Out of them, 83% patients had positive HRCT chest findings of COVID-19, 17% had negative HRCT chest findings; while 40.4% had positive and 59.6% had negative first PCR. Among the repeat second PCR, 19.6% had negative, 1.8% had positive PCR results; while 78.6% patients didn't undergo repeat PCR. The sensitivity, specificity, NPV, PPV and accuracy of HRCT chest was 92%, 23%, 81%, 45%, and 51%; while of first RT-PCR was 45%, 81%, 23%, 92% and 51%, respectively.CONCLUSION:
The sensitivity of HRCT chest is higher (92%) as compared to first RT-PCR (45%). Key Words COVID-19, RT-PCR, HRCT chest, Sensitivity, Specificity.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Tomography, X-Ray Computed
/
Reverse Transcriptase Polymerase Chain Reaction
/
Pandemics
/
SARS-CoV-2
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
English
Journal:
J Coll Physicians Surg Pak
Journal subject:
Medicine
Year:
2021
Document Type:
Article
Affiliation country:
Jcpsp.2021.01.S1
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