Your browser doesn't support javascript.
Treatment of unexplained coma and hypokinetic-rigid syndrome in a patient with COVID-19.
Roy, Devjit; Song, Justin; Awad, Nirvana; Zamudio, Paul.
  • Roy D; Department of Medicine, Montefiore Nyack Hospital, Nyack, NY, USA devjit.roy@gmail.com.
  • Song J; Department of Medicine, Albert Einstein - College of Medicine, Bronx, NY, USA.
  • Awad N; Department of Medicine, Albert Einstein - College of Medicine, Bronx, NY, USA.
  • Zamudio P; Department of Medicine, Montefiore Nyack Hospital, Nyack, NY, USA.
BMJ Case Rep ; 14(3)2021 Mar 02.
Article in English | MEDLINE | ID: covidwho-1115107
Semantic information from SemMedBD (by NLM)
1. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
2. Comatose PROCESS_OF Patients
Subject
Comatose
Predicate
PROCESS_OF
Object
Patients
3. Syndrome PROCESS_OF Patients
Subject
Syndrome
Predicate
PROCESS_OF
Object
Patients
4. Encephalopathies PROCESS_OF Patients
Subject
Encephalopathies
Predicate
PROCESS_OF
Object
Patients
5. prolonged hospitalization PROCESS_OF Patients
Subject
prolonged hospitalization
Predicate
PROCESS_OF
Object
Patients
6. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
7. Comatose PROCESS_OF Patients
Subject
Comatose
Predicate
PROCESS_OF
Object
Patients
8. Syndrome PROCESS_OF Patients
Subject
Syndrome
Predicate
PROCESS_OF
Object
Patients
9. Encephalopathies PROCESS_OF Patients
Subject
Encephalopathies
Predicate
PROCESS_OF
Object
Patients
10. prolonged hospitalization PROCESS_OF Patients
Subject
prolonged hospitalization
Predicate
PROCESS_OF
Object
Patients
ABSTRACT
The COVID-19 pandemic has dealt a devastating blow to healthcare systems globally. Approximately 3.2% of patients infected with COVID-19 require invasive ventilation during the course of the illness. Within this population, 25% of patients are affected with neurological manifestations. Among those who are affected by severe neurological manifestations, some may have acute cerebrovascular complications (5%), impaired consciousness (15%) or exhibit skeletal muscle hypokinesis (20%). The cause of the severe cognitive impairment and hypokinesis is unknown at this time. Potential causes include COVID-19 viral encephalopathy, toxic metabolic encephalopathy, post-intensive care unit syndrome and cerebrovascular pathology. We present a case of a 60 year old patient who sustained a prolonged hospitalization with COVID-19, had a cerebrovascular event and developed a persistent unexplained encephalopathy along with a hypokinetic state. He was treated successfully with modafinil and carbidopa/levodopa showing clinical improvement within 3-7 days and ultimately was able to successfully discharge home.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Rehabilitation / Brain Diseases / Carbidopa / Levodopa / Hypokinesia / Modafinil / Ischemic Stroke / SARS-CoV-2 / COVID-19 Subject: Rehabilitation / Brain Diseases / Carbidopa / Levodopa / Hypokinesia / Modafinil / Ischemic Stroke / SARS-CoV-2 / COVID-19 Type of study: Case report / Diagnostic study / Etiology study Language: English Clinical aspect: Prognosis Year: 2021

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Document Type: Article Main subject: Rehabilitation / Brain Diseases / Carbidopa / Levodopa / Hypokinesia / Modafinil / Ischemic Stroke / SARS-CoV-2 / COVID-19 Subject: Rehabilitation / Brain Diseases / Carbidopa / Levodopa / Hypokinesia / Modafinil / Ischemic Stroke / SARS-CoV-2 / COVID-19 Type of study: Case report / Diagnostic study / Etiology study Language: English Clinical aspect: Prognosis Year: 2021
...