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Value of D-dimer, C-reactive protein, procalcitonin, and blood routine test in assessing the prognosis of severe coronavirus disease 2019
Medical Journal of Wuhan University ; 42(2):233-236, 2021.
Article in Chinese | Scopus | ID: covidwho-1115573
ABSTRACT

Objective:

To investigate the value of D-dimer, C-reactive protein (CRP), Procalcitonin (PCT) and blood routine test in evaluating the prognosis of patients with severe coronavirus disease 2019 (COVID-19).

Methods:

A total of 54 severe COVID-19 patients were retrospectively studied, and were divided into death group (n=54) and survival group (n=31) according to the outcomes. The plasma D-dimer, CRP, PCT, and blood routine test of the two groups were analyzed and compared in order to clarify their relationship to the prognosis of severe COVID-19.

Results:

The time to initiation of disease days, age and proportion of comorbidity in death group were significantly longer or higher than in survival group (all P<0.05). The white blood cell counts and neutrophil counts levels in death group were significantly higher than in survival group (both P<0.05), while the lymphocyte counts levels in dead group were significantly lower than in survival group (P<0.05). D-dimer, CRP and PCT in death group were significantly higher than in survival group (all P<0.05). D-dimer was positively correlated to CRP (r=0.426, P<0.05), and negatively correlated with PCT (r=-0.217, P>0.05).

Conclusion:

D-dimer, CRP, white blood cell counts, and lymphocyte counts are valuable for prognosis evaluation of patients with severe COVID-19, and PCT also has certain prognostic value. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.

Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Wuhan University Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Wuhan University Year: 2021 Document Type: Article