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Clinical analysis of 17 cases of COVID-19 after operation
Medical Journal of Wuhan University ; 42(2):245-249, 2021.
Article in Chinese | Scopus | ID: covidwho-1115575
ABSTRACT

Objective:

To explore the risk factors and control methods of surgical operation during the outbreak of coronavirus disease 2019 (COVID-19), and to summarize the experience of prevention and treatment methods of COVID-19 under surgical conditions from a single center during the epidemic.

Methods:

The clinical data of 17 patients diagnosed as COVID-19 postoperatively in Renmin Hospital of Wuhan University from January 3 to January 22, 2020 were collected and analyzed. The diseases were classified according to the Chinese Diagnosis and Treatment of Novel Coronavirus Infected Pneumonia (5th trial edition). The mild and moderate type patients were incorporated into the non-severe group, while the severe and critical ones were categerized into the severe group. Then we compared the general information, clinical symptoms, laboratory test results, and outcomes between the two groups.

Results:

The clinical data of 3 339 patients underwent surgical operation were reviewed, and 17 patients were diagnosed as COVID-19 after operation, with a 0.51% incidence rate. Among them, 7 cases (41.2%) were severe, and 2 cases (11.8%) died of respiratory failure. The clinical manifestations were mainly fever (76.47%) and cough (58.82%). Laboratory examination results showed that in most patients, the leukocyte count was normal (70.59%), lymphocyte count was lower (88.24%), and C-reactive protein level was higher (88.24%). Immune function tests showed that cellular immune function was significantly impaired in some patients. Among them, 62.5%, 62.5% and 75% of the patients had decreased CD3 count, CD4 count and CD8 count. The percentage of severe COVID-19 cases in open surgery patients was significantly higher than that in minimally invasive surgery ones (71.43% vs 20%, P=0.034).

Conclusion:

The proportion of severe cases and mortality in COVID-19 patients undergone surgery are higher than those who haven't;and the severity rate of them receiving open surgery is higher than those performed minimally invasive surgery. During the epidemic, elective or confine surgery should be postponed and the indications for emergency surgery should be strictly accorded with;If an emergency surgery is inevitable, minimally invasive surgery should be selected as a priority. Postoperative screening of COVID-19 should be strengthened, while early, detection, early reporting, early isolation and early treatment should be applied to the infected patients. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.

Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Wuhan University Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: Chinese Journal: Medical Journal of Wuhan University Year: 2021 Document Type: Article