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Plasma as an alternative COVID-19 diagnostic specimen in a hospitalized patient negative for SARS-CoV-2 by nasopharyngeal swab.
Lawrence, Lauren; Stevens, Bryan A; Sahoo, Malaya K; Huang, ChunHong; Yamamoto, Fumiko; Röltgen, Katharina; Wirz, Oliver; Zehnder, James; Shi, Run-Zhang; Boyd, Scott D; Schoolnik, Gary; Pinsky, Benjamin A; Hogan, Catherine A.
  • Lawrence L; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Stevens BA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA; Clinical Virology Laboratory, Stanford Health Care, Stanford, CA, USA.
  • Sahoo MK; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Huang C; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Yamamoto F; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Röltgen K; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Wirz O; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Zehnder J; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Shi RZ; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Boyd SD; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
  • Schoolnik G; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • Pinsky BA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA; Clinical Virology Laboratory, Stanford Health Care, Stanford, CA, USA; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • Hogan CA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA; Clinical Virology Laboratory, Stanford Health Care, Stanford, CA, USA. Electronic address: hoganca@stanford.edu.
Diagn Microbiol Infect Dis ; 100(3): 115365, 2021 Jul.
Article in English | MEDLINE | ID: covidwho-1116561
ABSTRACT
We present the case of an inpatient with pneumonia and repeatedly negative nasopharyngeal SARS-CoV-2 testing. In such challenging cases, alternative diagnostic options include lower respiratory tract and plasma SARS-CoV-2 RNA testing, of which the latter may be particularly useful where bronchoscopy is deferred due to clinical factors or transmission risk.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Plasma / SARS-CoV-2 / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Limits: Adult / Humans / Male Language: English Journal: Diagn Microbiol Infect Dis Year: 2021 Document Type: Article Affiliation country: J.diagmicrobio.2021.115365

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Plasma / SARS-CoV-2 / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Limits: Adult / Humans / Male Language: English Journal: Diagn Microbiol Infect Dis Year: 2021 Document Type: Article Affiliation country: J.diagmicrobio.2021.115365