Environmental Determinants of Coronavirus Disease 2019 (COVID-19).
Curr Allergy Asthma Rep
; 21(3): 15, 2021 03 05.
Article
in English
| MEDLINE | ID: covidwho-1118276
ABSTRACT
PURPOSE FOR REVIEW Since the coronavirus SARS-CoV-2 outbreak in China in late 2019 turned into a global pandemic, numerous studies have reported associations between environmental factors, such as weather conditions and a range of air pollutants (particulate matter, nitrogen dioxide, ozone, etc.) and the first wave of COVID-19 cases. This review aims to offer a critical assessment of the role of environmental exposure risk factors on SARS-CoV-2 infections and COVID-19 disease severity. RECENT FINDINGS:
In this review, we provide a critical assessment of COVID-19 risk factors, identify gaps in our knowledge (e.g., indoor air pollution), and discuss methodological challenges of association and causation and the impact lockdowns had on air quality. In addition, we will draw attention to ethnic and socioeconomic factors driving viral transmission related to COVID-19. The complex role angiotensin-converting enzyme 2 (ACE2) plays in COVID-19 and future promising avenues of research are discussed. To demonstrate causality, we stress the need for future epidemiologic studies integrating personal air pollution exposures, detailed clinical COVID-19 data, and a range of socioeconomic factors, as well as in vitro and in vivo mechanistic studies.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Air Pollution, Indoor
/
Air Pollution
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Animals
/
Humans
Language:
English
Journal:
Curr Allergy Asthma Rep
Journal subject:
Allergy and Immunology
Year:
2021
Document Type:
Article
Affiliation country:
S11882-021-00993-1
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