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Consensus Statement on the Management of Duchenne Muscular Dystrophy in Saudi Arabia During the Coronavirus Disease 2019 Pandemic.
Bamaga, Ahmed K; Alghamdi, Fouad; Alshaikh, Nahla; Altwaijri, Waleed; Bashiri, Fahad A; Hundallah, Khalid; Abukhaled, Musaad; Muthaffar, Osama Y; Al-Mehmadi, Sameer; Jamaly, Tahani Ahmed; Al-Muhaizea, Mohammad A; Al-Saman, Abdulaziz.
  • Bamaga AK; Neurology Division, Pediatric Department, Faculty of Medicine, King Abdulaziz University Hospital, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Alghamdi F; Pediatric Department, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.
  • Alshaikh N; King Fahad Specialist Hospital, Dammam, Saudi Arabia.
  • Altwaijri W; Pediatric Department, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia.
  • Bashiri FA; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
  • Hundallah K; King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
  • Abukhaled M; Pediatric Department, King Saud Bin Abdulaziz University, Riyadh, Saudi Arabia.
  • Muthaffar OY; Pediatric Department, King Abdullah Specialized Children Hospital, Riyadh, Saudi Arabia.
  • Al-Mehmadi S; Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
  • Jamaly TA; Division of Neurology, Department of Pediatrics, King Saud University Medical City, Riyadh, Saudi Arabia.
  • Al-Muhaizea MA; Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
  • Al-Saman A; Department of Neuroscience, King Faisal Specialist Hospital and Research Centre, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Front Pediatr ; 9: 629549, 2021.
Article in English | MEDLINE | ID: covidwho-1120412
Semantic information from SemMedBD (by NLM)
1. COVID-19 CAUSES Challenge
Subject
COVID-19
Predicate
CAUSES
Object
Challenge
2. Muscular Dystroph PROCESS_OF C0030705
Subject
Muscular Dystroph
Predicate
PROCESS_OF
Object
C0030705
3. Paresis CAUSES Respiratory complication
Subject
Paresis
Predicate
CAUSES
Object
Respiratory complication
4. Respiratory complication COEXISTS_WITH Muscular Dystroph
Subject
Respiratory complication
Predicate
COEXISTS_WITH
Object
Muscular Dystroph
5. Disease PROCESS_OF Patients
Subject
Disease
Predicate
PROCESS_OF
Object
Patients
6. Angiotensin-Converting Enzyme Inhibitors ADMINISTERED_TO Patients
Subject
Angiotensin-Converting Enzyme Inhibitors
Predicate
ADMINISTERED_TO
Object
Patients
7. Angiotensin II receptor antagonist ADMINISTERED_TO Patients
Subject
Angiotensin II receptor antagonist
Predicate
ADMINISTERED_TO
Object
Patients
8. Respiratory complication PROCESS_OF Patients
Subject
Respiratory complication
Predicate
PROCESS_OF
Object
Patients
9. Multi-disciplinary team METHOD_OF Telemedicine
Subject
Multi-disciplinary team
Predicate
METHOD_OF
Object
Telemedicine
10. COVID-19 CAUSES Challenge
Subject
COVID-19
Predicate
CAUSES
Object
Challenge
11. Muscular Dystrophy, Duchenne PROCESS_OF Patients
Subject
Muscular Dystrophy, Duchenne
Predicate
PROCESS_OF
Object
Patients
12. Paresis CAUSES Respiratory complication
Subject
Paresis
Predicate
CAUSES
Object
Respiratory complication
13. Respiratory complication COEXISTS_WITH Muscular Dystrophy, Duchenne
Subject
Respiratory complication
Predicate
COEXISTS_WITH
Object
Muscular Dystrophy, Duchenne
14. Disease PROCESS_OF Patients
Subject
Disease
Predicate
PROCESS_OF
Object
Patients
15. Angiotensin-Converting Enzyme Inhibitors ADMINISTERED_TO Patients
Subject
Angiotensin-Converting Enzyme Inhibitors
Predicate
ADMINISTERED_TO
Object
Patients
16. Angiotensin II receptor antagonist ADMINISTERED_TO Patients
Subject
Angiotensin II receptor antagonist
Predicate
ADMINISTERED_TO
Object
Patients
17. Respiratory complication PROCESS_OF Patients
Subject
Respiratory complication
Predicate
PROCESS_OF
Object
Patients
18. Multi-disciplinary team METHOD_OF Telemedicine
Subject
Multi-disciplinary team
Predicate
METHOD_OF
Object
Telemedicine
ABSTRACT

Background:

The coronavirus disease 2019 (COVID-19) pandemic has caused overwhelming challenges in healthcare worldwide. During such an outbreak, some needs of high-risk groups who require regular follow-ups and long-term management are not met. The vulnerable populations include patients with Duchenne muscular dystrophy (DMD). Duchenne muscular dystrophy is characterized by respiratory complications caused by muscle weakness. Hence, patients with this condition are at high risk of severe diseases including COVID-19.

Methods:

To standardize care and provide optimal treatment to DMD patients in Saudi Arabia during the COVID-19 pandemic, a panel of experts including neurologists and pediatricians consolidated recommendations for healthcare professionals and caregivers.

Results:

During this pandemic, substituting unnecessary clinic visits with virtual clinic services was highly recommended, if possible, without compromising clinical outcomes. Duchenne muscular dystrophy patients with respiratory complications should be closely monitored, and those with cardiovascular complications must continue taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. Moreover, individualized home-based rehabilitation management was preferred. Glucocorticoid and new gene correction therapies should be continued. However, new gene correction therapy must be post-poned in newly diagnosed patients. A multidisciplinary decision was required before the initiation of hydroxychloroquine based on the COVID-19 treatment protocol.

Conclusion:

COVID-19 has caused challenges and transformed access to health care. However, these limitations have provided opportunities for the health care system to adapt. Further, telemedicine has become a reliable platform for follow-up appointments that should be conducted by a multidisciplinary team including physicians, dieticians, and physical therapists.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Clinical Practice Guide / Prognostic study / Randomized controlled trials Language: English Journal: Front Pediatr Year: 2021 Document Type: Article Affiliation country: Fped.2021.629549

Full text: Available Collection: International databases Database: MEDLINE Type of study: Clinical Practice Guide / Prognostic study / Randomized controlled trials Language: English Journal: Front Pediatr Year: 2021 Document Type: Article Affiliation country: Fped.2021.629549