Frequency of asthma exacerbation in children during the coronavirus disease pandemic with strict mitigative countermeasures.
Pediatr Pulmonol
; 56(6): 1455-1463, 2021 06.
Article
in English
| MEDLINE | ID: covidwho-1121025
ABSTRACT
BACKGROUND:
Strict countermeasures for coronavirus disease (COVID-19) were undertaken in China without knowing their influence on asthma.OBJECTIVE:
To investigate the associations between the frequencies of asthma exacerbations and respiratory infections and air pollutants before and during the COVID-19 pandemic, which were direct consequences of countermeasures undertaken for the pandemic.METHODS:
Asthma exacerbations and respiratory infections among hospitalized children in the permanent population of Guangzhou City, China, from February to June 2016-2019 (before the pandemic) to February to June 2020 (during the pandemic) were collected in this cross-sectional study in Guangzhou.RESULTS:
The number of asthma exacerbation cases per month documented in the Guangzhou Women and Children's Hospital before (median 13.5; range 0-48) and during (median 20; range 0-34) the mitigative response to the COVID-19 pandemic was similar. The frequency of severe asthma exacerbation cases per month decreased, whereas that of mild asthma exacerbation cases per year increased (p = .004). The number of patients hospitalized with infectious respiratory diseases decreased from 146 (range 90-172) per month before the pandemic to 42 (range 33-57) per month during the pandemic (p = .004). Most pathogens and air pollutants decreased during the COVID-19 pandemic. The frequency of severe asthma exacerbations positively correlated to that of respiratory infections in children, but did not correlate to air pollutants.CONCLUSION:
Strict countermeasures undertaken for the pandemic were associated with a decreased the frequency of infectious respiratory diseases and severe asthma exacerbations among urban children.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Asthma
/
SARS-CoV-2
/
COVID-19
Type of study:
Observational study
/
Randomized controlled trials
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Pediatr Pulmonol
Journal subject:
Pediatrics
Year:
2021
Document Type:
Article
Affiliation country:
Ppul.25335
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