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Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib.
Frankel, Arthur E; Reddy, Renuka; DeSuza, Kayla R; Deeb, Khaled; Carlin, Aaron F; Smith, Davey; Xie, Yushuang; Naik, Eknath; Silver, Richard T; Hasselbalch, Hans C.
  • Frankel AE; Department of Medicine West Palm Beach VA Medical Center West Palm Beach FL USA.
  • Reddy R; Department of Medicine West Palm Beach VA Medical Center West Palm Beach FL USA.
  • DeSuza KR; Department of Medicine West Palm Beach VA Medical Center West Palm Beach FL USA.
  • Deeb K; Department of Medicine West Palm Beach VA Medical Center West Palm Beach FL USA.
  • Carlin AF; Division of Infectious Disease UCSD Medical School San Diego CA USA.
  • Smith D; Division of Infectious Disease UCSD Medical School San Diego CA USA.
  • Xie Y; Department of Medicine West Palm Beach VA Medical Center West Palm Beach FL USA.
  • Naik E; Department of Medicine West Palm Beach VA Medical Center West Palm Beach FL USA.
  • Silver RT; Division of Hematology and Medical Oncology Weill Cornell Medicine New York NY USA.
  • Hasselbalch HC; Department of Hematology Zealand University Hospital Roskilde Denmark.
Clin Case Rep ; 9(4): 2228-2235, 2021 Apr.
Article in English | MEDLINE | ID: covidwho-1122024
ABSTRACT
An 83-year-old female had asymptomatic SARS-CoV-2 infection while taking ruxolitinib. She remained RT-PCR positive for viral RNA for >120 days, and Pegylated interferon for 4 weeks led to viral RNA clearance. The observations support combination therapy of ruxolitinib + interferon for COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Observational study / Prognostic study Language: English Journal: Clin Case Rep Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Observational study / Prognostic study Language: English Journal: Clin Case Rep Year: 2021 Document Type: Article