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Diagnostic Accuracy of the Panbio Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Rapid Test Compared with Reverse-Transcriptase Polymerase Chain Reaction Testing of Nasopharyngeal Samples in the Pediatric Population.
Villaverde, Serena; Domínguez-Rodríguez, Sara; Sabrido, Gema; Pérez-Jorge, Conchita; Plata, Marta; Romero, María Pilar; Grasa, Carlos Daniel; Jiménez, Ana Belén; Heras, Elena; Broncano, Antonio; Núñez, María Del Mar; Illán, Marta; Merino, Paloma; Soto, Beatriz; Molina-Arana, David; Bermejo, Amanda; Mendoza, Pablo; Gijón, Manuel; Pérez-Moneo, Begoña; Moraleda, Cinta; Tagarro, Alfredo.
  • Villaverde S; Pediatric Research and Clinical Trials Unit (UPIC), Instituto de Investigación Sanitaria Hospital 12 de Octubre (IMAS12), Fundación para la Investigación Biomédica Hospital 12 de Octubre, Madrid, Spain. Electronic address: serenavillaverde@outlook.es.
  • Domínguez-Rodríguez S; Pediatric Research and Clinical Trials Unit (UPIC), Instituto de Investigación Sanitaria Hospital 12 de Octubre (IMAS12), Fundación para la Investigación Biomédica Hospital 12 de Octubre, Madrid, Spain.
  • Sabrido G; Pediatrics Department, Hospital Universitario Rey Juan Carlos, Móstoles, Spain.
  • Pérez-Jorge C; Microbiology Department, Hospital Universitario Rey Juan Carlos, Móstoles, Spain.
  • Plata M; Pediatrics Department, Hospital Universitario La Paz, Madrid, Spain; Emergency Department, Hospital Universitario La Paz, Madrid, Spain.
  • Romero MP; Microbiology Department, Hospital Universitario La Paz, Madrid, Spain.
  • Grasa CD; Pediatrics, Hospital Universitario La Paz, Instituto de Investigación Hospital La Paz (IDIPAZ), Madrid, Spain; Infectious and Tropical Diseases, Hospital Universitario La Paz, Instituto de Investigación Hospital La Paz (IDIPAZ), Madrid, Spain.
  • Jiménez AB; Pediatrics Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
  • Heras E; Pediatrics Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
  • Broncano A; Microbiology Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
  • Núñez MDM; Pediatrics Emergency Department, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
  • Illán M; Pediatrics Department, Hospital Universitario Clínico San Carlos, Madrid, Spain.
  • Merino P; Microbiology Department, Hospital Universitario Clínico San Carlos, Madrid, Spain.
  • Soto B; Pediatrics Department, Hospital Universitario de Getafe, Getafe, Spain.
  • Molina-Arana D; Microbiology Department, Hospital Universitario de Getafe, Getafe, Spain.
  • Bermejo A; Pediatrics Department, Hospital Universitario de Móstoles, Móstoles, Spain.
  • Mendoza P; Microbiology Department, Hospital Universitario de Móstoles, Móstoles, Spain.
  • Gijón M; Pediatrics Emergency Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Pérez-Moneo B; Pediatrics Department, Hospital Universitario Infanta Leonor, Madrid, Spain.
  • Moraleda C; Pediatric Research and Clinical Trials Unit (UPIC), Instituto de Investigación Sanitaria Hospital 12 de Octubre (IMAS12), Fundación para la Investigación Biomédica Hospital 12 de Octubre, Madrid, Spain; Pediatric Infectious Diseases Unit, Department of Pediatrics, Hospital Universitario 12 de Octubr
  • Tagarro A; Pediatric Research and Clinical Trials Unit (UPIC), Instituto de Investigación Sanitaria Hospital 12 de Octubre (IMAS12), Fundación para la Investigación Biomédica Hospital 12 de Octubre, Madrid, Spain; Pediatrics Department, Hospital Universitario Infanta Sofía, Madrid, Spain.
J Pediatr ; 232: 287-289.e4, 2021 05.
Article in English | MEDLINE | ID: covidwho-1126937
ABSTRACT
We conducted a multicenter clinical validity study of the Panbio coronavirus disease 2019 Antigen Rapid Test of nasopharyngeal samples in pediatric patients with coronavirus disease 2019-compatible symptoms of ≤5 days of evolution. Our study showed limited accuracy in nasopharyngeal antigen testing overall sensitivity was 45.4%, and 99.8% of specificity, positive-predictive value was 92.5%.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: DNA, Viral / Nasopharynx / Reverse Transcriptase Polymerase Chain Reaction / SARS-CoV-2 / COVID-19 / Antigens, Viral Type of study: Diagnostic study / Prognostic study Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: English Journal: J Pediatr Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: DNA, Viral / Nasopharynx / Reverse Transcriptase Polymerase Chain Reaction / SARS-CoV-2 / COVID-19 / Antigens, Viral Type of study: Diagnostic study / Prognostic study Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: English Journal: J Pediatr Year: 2021 Document Type: Article